The stoichiometric ratio 2:1 mix of 1-phenylpiperazine and oxalic acid dihydrate followed by slow evaporation results in a new material, bis(4-phenylpiperazin-1-ium) oxalate dihydrate, with the general chemical formula (C10H15N2)2(C2O4).2H2O, indicated PPOXH. title compound’s asymmetric unit three-dimensional network have been determined single crystal X-ray diffraction. Intermolecular O-H…O, N...

This study aimed to contribute to the dimensional approach to personality pathology by addressing the applicability of a personality pathology questionnaire, originally developed for adults, in adolescent samples. The psychometric properties of the Dimensional Assessment of Personality Pathology-Basic Questionnaire for Adolescents (DAPP-BQ-A) were studied in two samples including 170 adolescent...

The effect of the non-selective 5-HT2C receptor agonist trifluoromethyl-phenylpiperazine (TFMPP, 0.75, 1.5 and 3.0 microg) and the preferential 5-HT2C agonist 6-chloro-2(1-piperazinyl)pyrazine (MK-212, 0.1, 0.3 and 1.0 microg) microinjected into the ventral or dorsal hippocampus was investigated in anxiety measures of rats exposed to the elevated plus-maze test. Ventral hippocampal (VH) microin...

A series of new 1,3-dimethyl-7-phenylalkyl-8-[3-(4-phenyl-1-piperazinyl)propylamino]-purine-2,6-dione derivatives (10-16) was synthesized and their 5-HTIA and 5-HT2A receptor affinities were determined. It was found that compounds with the phenylpropyl substituent in position 7 of purine-2,6-dione (12, 14 and 16), or with phenylmethyl in position 7 and 2-OCH3 in the phenylpiperazine part (13) s...

The electrochemical behavior of Ru(bpy),2+ (bpy = 2,2'-bipyridine) contained in 2-"thick films of the perfluorosulfonate polymer Nafion on glassy carbon is described. The apparent diffusion coefficient, D, , for the 2+ and 3+ forms was determined by potential-step chronoamperometric measurements to be (5 & 2) X cm*s-l. Dapp for the 2+ form was independent of loading of R ~ ( b p y ) , ~ + in th...