Utilizing somatic cell hybridization, we have developed a monoclonal antibody that interacts only with cells of the monocyte/macrophage (M phi) line and not with other myeloid or lymphoid cells. This antibody detects a 120,000-dalton determinant present on 37 +/- 2.8% of the peripheral blood M phi from several (HLA-DR)-disparate individuals and only depicts a subpopulation (approximately 30%) o...

Increasing evidence suggests that gamma interferon (IFN-gamma) is the major or sole factor in human lymphokines which activates blood monocyte-derived macrophages (M phi) to inhibit or kill Toxoplasma gondii and certain other intracellular pathogens. In the current studies, we found that IFN-gamma effectively activated tissue M phi from adults (peritoneal M phi) and from newborns (placental M p...

We examine the persistent random motion of self-propelled rods (SPR) as a function of the area fraction phi and study the effect of steric interactions on their diffusion properties. SPR of length l and width w are fabricated with a spherocylindrical head attached to a beaded chain tail, and show directed motion on a vibrated substrate. The mean square displacement (MSD) on the substrate grows ...

The presence of macromolecules in cells geometrically restricts the available space for poplypeptide chains. To study the effects of macromolecular crowding on folding thermodynamics and kinetics, we used an off-lattice model of the all-beta-sheet WW domain in the presence of large spherical particles whose interaction with the polypeptide chain is purely repulsive. At all volume fractions, phi...

In order to determine if human LAK cells were cytotoxic against autologous AM phi, we studied the ability of human peripheral blood MNCs, stimulated in vitro with recombinant human IL-2, to lyse AM phi in a four-hour 51Cr-release assay. These cells showed significant cytotoxicity against autologous AM phi. The AM phi which had been cultured for four days served as better targets than freshly is...

Cells within solid tumors are known to exist in a microenvironment that may be acidic and depend on membrane-based mechanisms (Na+/H+ antiport and Na+-dependent Cl-/HCO3- exchanger) that regulate intracellular pH (pHi). We have used the fluorescent pH indicator 2',7'-bis-(2-carboxyethyl) 5 (and 6)-carboxyfluorescein and flow cytometry to study the distribution of pHi and the activity of these p...

In this paper, we study the iterations of quasi $phi$-nonexpansive mappings and its applications in Banach spaces. At the first, we prove strong convergence of the sequence generated by the hybrid proximal point method to a common fixed point of a family of quasi $phi$-nonexpansive mappings.  Then, we give  applications of our main results in equilibrium problems.

Black Student Movement [2] Minority Business Student Alliance [3] National Panhellenic Council (Black Greek Council) [4] Carolina Indian Circle [5] Carolina Hispanic Association [6] Asian Student Association [7] Black Sororities and Fraternities Alpha Kappa Alpha [8] Omega Psi Phi [9] Alpha Phi Alpha [10] Phi Beta Sigma [11] Delta Sigma Theta [12] Sigma Gamma Rho [13] Kappa Alpha Psi [14] Zeta ...

PURPOSE OF REVIEW The purpose of this review was to provide current data on clinical presentation, diagnosis, and treatment of primary HIV infection (PHI). RECENT FINDINGS In 65 to 95% of cases, PHI causes acute retroviral syndrome presenting with unspecific flu-like symptoms. Symptomatic PHI was associated with a faster clinical and immunological progression of HIV infection. Point-of-care t...