نتایج جستجو برای: phosphohydrolase

تعداد نتایج: 697  

Journal: :Clinical chemistry 1988
D Rusciano A Berardi C Ceccarini B Terrana

We report a protocol for concomitant purification to homogeneity of both prostatic acid phosphatase [orthophosphoric-monoester phosphohydrolase (acid optimum), EC 3.1.3.2] and prostate-specific antigen, from human seminal fluid. The method requires only two chromatographic steps: passage through an Affigel-Blue column and gel filtration HPLC. This is a fast, efficient procedure for purification...

Journal: :The Journal of antibiotics 2002
Yoon-Jeong Kim Hiroyuki Nishida Chang-Hong Pang Toshiyuki Saito Shinichi Sakemi Hiroko Tonai-Kachi Nobuji Yoshikawa Maria A Vanvolkenburg Janice C Parker Yasuhiro Kojima

A new D-glucose-6-phosphate phosphohydrolase (G6Pase) inhibitor, CJ-21,164 (1) was isolated from the fermentation broth of the fungus Chloridium sp. CL48903. The structure was elucidated to be a novel tetramer of the salicylic acid derivatives by spectroscopic analyses. Compound I inhibited G6Pase in rat liver microsomes with an IC50 of 1.6 microM. Glucose output from hepatocytes isolated from ...

Journal: :Zeitschrift fur Naturforschung. C, Journal of biosciences 1987
B Ofenloch-Hähnle K Eisele

Inhibition of 3':5'-cyclic-AMP-5'-nucleotidohydrolase (EC 3.1.4.17) type II (cAMP-phosphodiesterase) by sodium molybdate was studied: While determination of inorganic phosphate and 5'-ribonucleotide phosphohydrolase (5'-nucleotidase) (EC 3.1.3.5) activity was not disturbed by sodium molybdate in concentrations up to 10 mM, cAMP-phosphodiesterase was inhibited by millimolar concentrations of mol...

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