P2X1 receptors for ATP contribute to signalling in a variety of cell types and following stimulation undergo rapid desensitisation (within 1 s), and require approximately 5 min to recover. In HEK293 cells P2X1 receptors C-terminally tagged with enhanced green fluorescent protein (P2X1-eGFP) were predominantly expressed at the cell surface. Following > 90% photo-bleaching of P2X1-eGFP within a 6...

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Nifedipine (NIF), a 1,4-dihydropyridine calcium channel antagonist, undergoes photo-degradation to dehydro-nifedipine (DNIF) upon exposure to ultraviolet (UV) light and to the nitroso analogue of dehydro-nifedipine (NDNIF) when exposed to sunlight or some kinds of artificial lights. NIF photo-degradation products do not contribute to clinical activity, thus prevention of photo-degradation of NI...

We propose a unified framework to study the walk problem in a polygonal area by two collaborative guards. A walk is conducted by the two mobile guards on the area’s boundary. They start at an initial boundary point, move along the boundary, and may possibly meet together again at an ending boundary point. It is required that the two guards maintain their mutual visibility at all times. Dependin...

A review of methods for volumetric scene reconstruction from multiple views is presented. Occupancy descriptions of the voxels in a scene volume are constructed using shape-from-silhouette techniques for binary images, and shapefrom-photo-consistency combined with visibility testing for color images.

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Inspired by the recent Democratic National Primary, we consider settings in which the members of a distributed population must balance their individual preferences over candidates with a requirement to quickly achieve collective unity. We formalize such settings as the “Democratic Primary Problem” (DPP) over an undirected graph, whose local structure models the social influences acting on

BACKGROUND The use of visible or near infrared spectral light alone for the purpose of skin rejuvenation has been previously reported. A method of light emitting diode (LED) photo rejuvenation incorporating a combination of these wavelengths and thus compounding their distinct stimulation of cellular components is proposed.Objective. To assess the efficacy and local tolerability of combination ...

Because human emotion varies greatly among individuals and is a qualitative factor, measuring it with any degree of accuracy is very difficult. Heart rate variability (HRV), which is used in evaluations of the autonomic nervous system (ANS), is used to evaluate human emotions. This study examines the validity of HRV as a tool to evaluate emotions using the International Affective Picture System...