Melanopsin (OPN4) is a photoreceptive molecule regulating circadian systems in mammals. Previous studies from our laboratory have shown that co-localized dopamine-melatonin (DA-MEL) neurons in the hypothalamic premammillary nucleus (PMM) are putatively photosensitive and exhibit circadian rhythms in DAergic and MELergic activities. This study investigates turkey OPN4x (tOPN4x) mRNA distribution...

Clinically ineffective transplatin was converted into a photosensitive prodrug for drug delivery and triggered release to overcome cisplatin resistance.

The weak photon absorption and fast carrier kinetics of graphene limit its application in photodetection. This limitation can be overcome by introducing photosensitive nanostructures to graphene. Herein we report the synthesis of a ZnO nanorod/graphene heterostructure by a facile in situ solution growth method. By combining the attributes of photosensitive ZnO nanorods and highly conductive gra...

Boron and germanium doped highly photosensitive cladding is used in a novel design to achieve photosensitive Er/Yb doped fibres, enabling short strong gratings (length = 1 cm, reflectivity > 99%) to be written without hydrogenation. The high absorption at 980 nm in Er/Yb fibres allows efficient pump absorption over a short device length, ideal for achieving highly efficient single frequency fib...

Clonazepam was added to the treatment of patients with poorly controlled epilepsy in a double-blind trial and an open trial. Considerable improvement occurred with patients with myoclonic jerks and tonic-clonic convulsions, and with photosensitive epilepsy. Patients with atypical petit mal and focal epilepsies also improved. Drowsiness was initially common but lasted only a short time. No evide...