A simple, precise and rapid high-performance thin-layer chromatographic method has been developed for the estimation of phyllanthin (1) and hypophyllanthin (2), the important lignans of Phyllanthus species, especially Phyllanthus amarus. Separation of 1 and 2 was carried out on silica gel 60 F254 layers eluted with hexane:acetone:ethyl acetate (74:12:8), and the analytes were visualised through...

The plants of the genus Phyllanthus (Euphorbiaceae) have been used as traditional medicinal materials for a long time in China, India, Brazil, and the Southeast Asian countries. They can be used for the treatment of digestive disease, jaundice, and renal calculus. This review discusses the ethnopharmacological, phytochemical, and pharmacological studies of Phyllanthus over the past few decades....

the aim of this study was to investigate the effects of ethanolic extract of the whole plant of phyllanthus rheedii wight p.rheedii as antihyperglycemic, antihyperlipidemic and antioxidant effect in streptozotocin (stz) induced diabetic rats. male wistar rats were administered p.rheedii (250 mg/kg) orally for 21 days and blood glucose level was measured weekly. at the end of 21 days, the serum ...

OBJECTIVE This study was designed to investigate the potential Phyllanthus niruri (P. niruri ) extracts in promotion of hair growth. MATERIALS AND METHODS Here, we studied the hair growth promoting activity of petroleum ether extract of P. niruri following its topical administration. Alopecia was induced in albino rats by subcutaneous administration of testosterone for 21 days. Evaluation of ...

Catalase is an essential antioxidant enzyme that is well characterized from microbial and animal sources. The structure of plant catalase is unknown. Therefore, it is of interest to understand the functional and structural characteristics of catalase from an Indian gooseberry, Phyllanthus emblica (or Emblica officinalis). Hence, catalase from P. emblica was cloned in pUC18 plasmid, sequenced an...

In the present investigation, Emblica officinalis Gaerth. Syn Phyllanthus emblica linn. has been selected on account of its large scale use in manufacture of indigenous drugs. Among the various fungal, species, Aspergillus flavus was the most dominant and frequent species in most of food stuffs studied. The total population of Aspergillus. flavus was recorded in range of 20.30 × 10(3) - 89.50 ×...

General phytochemical screening of Phyllanthus amarus (Euphorbiaceae) revealed the presence of Saponin, tannins, glycoside and alkaloids etc. The aim of this study is to identify and characterize the bioactive principle from the plant. It has wide folk medicinal uses. The isolation and characterization of Phytoconstituents was done from the methanolic extract by the gradient fractionation metho...

Phyllanthus emblica L. (amla) has been used in Ayurveda as a potent rasayan for treatment of hepatic disorders. Most of the pharmacological studies, however, are largely focused on PE fruit, while the rest of the parts of PE, particularly, bark, remain underinvestigated. Therefore, we aimed to investigate the protective effect of the hydroalcoholic extract of Phyllanthus emblica bark (PEE) in e...

Phyllanthus amarus is an indigenous medicinal plant, with a folk reputation as hypoglycemic agent in Central and Southern India. In the present investigation hypoglycemic activity of ethanolic leaf extract of Phyllanthus amarus was evaluated using alloxan induced hyperglycemic mice. Blood glucose levels of all the mice of each group were tested before the treatments on fasting mice and then tes...

Objective: To assess the hepatoprotective effect of ethanolic extract of leaves and stem of Phyllanthus amarus and ethanolic extract of leaves of Tylophora indica against Isoniazid induced liver toxicity in experimental animals. Methods: Liver toxicity was induced by administering Isoniazid 27mg/kg orally for 30 days in Wistar albino rats. Ethanolic (90%) extracts of Phyllanthus amarus (PAEE) a...