Objective: The current study was designed to explore the hepatoprotective activity of Phyllanthus niruri (PN) alkaloid fraction in induced hepatitis in rats. Methods: The rats are divided into 5 groups as per the experimental design. Pre alkaloid treatment of PN was given to the hepatitis rats for 21 d. After completion of the treatment, the serum was collected, and biochemical analysis was car...

Medicinal herbs are significant source of pharmaceutical drugs. Latest trends have shown increasing demand of phytodrugs and some medicinal herbs have proven hepatotprotective potential. Silymarin, a flavonol lignan mixture) extracted from the Silybum marianum (milk thistle) is a popular remedy for hepatic diseases. Today every herbal company is marketing formulations for liver disorders but th...

The aqueous, different solvent extracts and isolated constituents of eight higher medicinal plants viz., Argemone mexicana, Caesalpinia coriaria, Decalepis hamiltonii, Euphorbia tirucalli, Leucas aspera, Phyllanthus amarus, Phyllanthus niruri, Tinospora cordifolia and Tribulus terrestris were screened in vitro for antibacterial activity by cup diffusion method against eleven human pathogenic ba...

2Department of Physiology, School of Pharmaceutical SciencesUniversiti Sains Malaysia, 11800 Minden, Penang, Malaysia. A b s t r a c t The purpose of this research was to study of physicochemical properties of the extracts and to develop and validate HPLC method in order to study their solubility in organic and aqueous vehicles and partition coefficients. The physicochemical characteristics suc...

This study aimed to evaluate the effects of aqueous extracts of dried Phyllanthus niruri L. (stonebreaker) leaves on Allium cepa L. root meristem cells at four concentrations, 0.02 (usual concentration), 0.04, 0.06 and 0.08mg/mL and exposure times of 24 and 48 hours. For each concentration we used a group of five onion bulbs that were first embedded in distilled water and then transferred to th...

Phyllanthus niruri L. is a small annual plant grows up to 30-40 cm tall. It an herbaceous that widely distributed in the tropical and sub-tropical regions. The aerial parts of P. growing Bangladesh were investigated for moisture content ash content, total phenolic flavonoid antioxidant capacity (TAC), cytotoxicity, relative fatty acid compositions antibacterial activity. dried leaves 5 7%, resp...