Physalis is an herbaceous species native to the Andes region. Currently, it cultivated in various Brazilian states due economic interest of growers for this new fruit. plants grown field showed symptoms shoot proliferation, leaf malformation, and chlorosis. Since these are commonly induced by phytoplasmas, study investigated confirm presence prokaryotes symptomatic plants. After DNA extraction ...

AIM To investigate the effects of Ground Cherry (Physalis angulata L.) standardized supercritical CO2 extract in trinitrobenzenesulphonic acid (TNBS) model of rat intestinal inflammation. METHODS The animals were divided into groups that received vehicle or P. angulata extract (PACO2) orally at the doses 25, 50 and 100 mg/kg daily by 5 d before TNBS damage. Protective effects of PACO2 were as...

BACKGROUND Leishmaniasis is an infectious disease caused by various species of the protozoan parasites of the Leishmania genus and transmitted by phlebotomine sandflies. The protozoa multiply in phagocytic cells, mainly macrophages, which play an important role defending the organism from pathogens. The most effective treatment for leishmaniasis is the chemotherapy and besides the high cost, th...

Physalis minima Linn. (Family  Solanaceae) is commonly known as Ground Cherry or Sunberry. It is traditionally used as diuretic, purgative, analgesic, anthelmentic, febrifuge, vermifuge, abortificient, etc. Many steroidal lactones have been identified from the plant and it has been reported to possess antifertility, hypoglycemic, cytotoxic, antiulcer, antibacterial, anti-inflammatory, analgesi...

O gênero Physalis é bastante difundido no mundo, por conta dos seu sabor diferenciado, características medicinais e valor nutricional (vitaminas A, C, fósforo, ferro, flavonoides, alcaloides, fitoesteroides, carotenoides, compostos bioativos, entre outros) (SALGADO, ARANA, 2013; MAMEDOV et al., 2017; MOKHTAR 2018).

Fourteen new withanolides, 1-14, named withalongolides A-N, respectively, were isolated from the aerial parts of Physalis longifolia together with eight known compounds (15-22). The structures of compounds 1-14 were elucidated through spectroscopic techniques and chemical methods. In addition, the structures of withanolides 1, 2, 3, and 6 were confirmed by X-ray crystallographic analysis. Using...