Introduction It has been said that pigmentation of the skin is the most distinctive feature of Addison's disease (British Medical Journal, 1963) and that no other clinical feature is as useful diagnostically (Dunlop, 1963). Four cases are presented where no pigmentation was found. The difficulties in diagnosis are discussed and it is suggested that Addison's disease without pigmentation is comm...

The severity of inflammation in sympathetic ophthalmia is related to the degree of pigmentation, and the granulomatous response seems to be related to pigmentation. Eosinophilia is also associated with pigmentation, but this association appears to be fortuitous and is a result of the association of eosinophilia with severity of the inflammation.

this study was conducted to examine morphometric and meristic characteristics alongside pigmentation patterns of bream larvae, abramis brama orientalis, in four stages of larval development. morphological characters including total length (tl), standard length (sl), notochord length (nl), head length (hl), head depth (hd), eye diameter (ed) and mouth width (mw) were examined from hatching time ...

Near-infrared fluorescence imaging (NIRFI) and far-red fluorescence imaging (FRFI) were used to investigate effects of depilation-induced skin pigmentation and diet-induced background fluorescence on fluorescent signal amplitude and lymphatic contraction frequency in C57BL6 mice. Far-red fluorescent signal amplitude, but not frequency, was affected by diet-induced fluorescence, which was remove...

Rates of skin cancer continue to increase despite the improved use of traditional sunscreens to minimize damage from ultraviolet radiation. The public perception of tanned skin as being healthy and desirable, combined with the rising demand for treatments to repair irregular skin pigmentation and the desire to increase or decrease constitutive skin pigmentation, arouses great interest pharmaceu...

BACKGROUND AND AIM: Oral pigmentation is a condition in which the color of oral mucosa such as gingival mucosa changes. Some exogenous and endogenous factors may lead to oral pigmentation. Secondhand smoke (SHS) or environmental tobacco smoke (ETS) is indirect smoking of an active smoker’s exhalation that can lead to cardiovascular, respiratory system, and some...

introduction: it has been shown that low levels of pigmentation increase susceptibility to noise-induced hearing loss in humans. for this reason, white populations develop more pronounced noise- induced hearing loss in comparison to black populations. similarly, blue-eyed individuals exhibit greater temporary threshold shift than brown-eyed subjects; still, no strong correlation has been verifi...

Drosophila polymorpha is a widespread species that exhibits abdominal pigmentation variation throughout its range. To gain insight into this variation we combined phenotypic and genotypic data to test a series of nested hypotheses. First, we tested the null hypothesis that geographic variation in pigmentation is due to neutral factors. We used nested clade analysis to examine the distribution o...

The significance of human cutaneous pigmentation lies in its protective role against sun-induced DNA damage and photocarcinogenesis. Fair skin and red hair are characterized by a low eumelanin to pheomelanin ratio, and have been associated with increased risk of skin cancer. Cutaneous pigmentation is a complex genetic trait, with more than 120 genes involved in its regulation, among which the m...