Background Methotrexate (MTX) is the cornerstone in pharmacological treatment of rheumatoid arthritis (RA) patients. However, medication adherence to MTX not ideal, which might lead suboptimal outcomes. Consequently instruments assess non-adherence are warranted detect and intervene on non-adherence. To date there no consensus best method determine MTX. Objectives The aim this study was correla...

BACKGROUND Understanding contraception from the perspective of the user may help to improve compliance. The aim of this project was to determine the factors that influence the noncompliance in young women that use combined hormonal contraceptives (pill, patch or vaginal ring). METHODS A nationwide cross-sectional multicenter epidemiology study. Physicians [obstetricians/gynecologists]) record...

In the late 1950's the pioneering works of dedicated scientists and researchers led to the first field trials of the hormonal steroids as oral contraceptives. Continuing excellent research in many countries have established the Pill as an extremely reliable, reversible and acceptable means of birth control. Some 200 million women in the world today have relied on/or are using the Pill for famil...

The study aimed to develop and validate an instrument capable of measuring non-adherence to drug treatment in its multiple dimensions. The Questionário de Adesão a Medicamentos (Adherence to Medicines Questionnaire) with three questions was applied to 46 people with arterial hypertension in the city of Blumenau, Southern Brazil, in 2006. Non-adherence measures obtained were compared to four oth...

BACKGROUND The multinational CHOICE (Contraceptive Health Research Of Informed Choice Experience) study evaluated the effects of structured counseling on women's contraceptive decisions, their reasons for making those decisions, and their perceptions of combined hormonal contraceptive (CHC) methods in eleven countries. The aim of this paper to present data from the 1,802 women participating in ...

BACKGROUND Combined oral contraception (COC, 'the pill') remains the most prescribed method of contraception in the UK. Although a variety of regimens for taking monophasic COC are held to be clinically safe, women are not routinely counselled about these choices and there is a lack of evidence on how to provide this information to women. AIM To assess the usefulness and feasibility of includ...

Background. Regular clinic attendance for antiretroviral (ARV) drug refills is important for successful clinical outcomes in HIV management. Methods. Clinic attendance for ARV drug refills and medication adherence using a clinic-based pill count in 392 adult patients receiving antiretroviral therapy (ART) in a district hospital in Uganda were prospectively monitored over a 28-week period. Resul...

Adherence to HAART medication regimens is vital to maintaining suppression of HIV, but persons with HIV face many challenges to adhering consistently to HIV medication regimens. This is particularly true for persons who live in geographically-isolated areas or who have significant levels of cognitive compromise. A videophone-based version of Reynolds' HAART CARE (HC) telephone intervention for ...

OBJECTIVE To assess the contraceptive effectiveness of condoms versus oral contraceptive pills and estimate the reproductive consequences of a major shift from pill to condom use. METHODS Secondary analysis was performed on nationally representative cross-sectional surveys of women in 16 developing countries. FINDINGS In the 16 countries, the median per cent of married couples currently usi...