results during the 3 months study, in the placebo group, systolic bp (sbp) increased with 6.3 mmhg and diastolic bp (dbp) increased with 4.6 mmhg, changes which were significant. after the 3 months, the effect of garlic on sbp, after adjusting for baseline value, was significant, and this effect was more significant in hypertensive patients. plasma lipids and lipoproteins did not change signific...

Our understanding and conceptualization of the placebo effect has shifted in emphasis from a focus on the inert content of a physical placebo agent to the overall simulation of a therapeutic intervention. Research has identified many types of placebo responses driven by different mechanisms depending on the particular context wherein the placebo is given. Some placebo responses, such as analges...

to investigate the effect of vitamin e supplementation on the response of intercellular adhesion molecule-1 (icam-1) to exhaustive exercise, 16 active men were selected and divided into supplementation and placebo groups based on vo2max. the subjects in each group completed 65 minutes of exhaustive exercise after14 days of supplementation. blood samples were collected before supplementation and...

abstract background: fatigue is the most common side effect of chemotherapy in children with acute lymphoblastic leukemia (all).acupressure is one of the most popular non‑pharmacologic methods used to reduce fatigue in other settings. the aim of the study was to evaluate the effect of acupressure on reducing fatigue among children with all compared with a placebo treatment. materials and method...

BACKGROUND For many years, placebo has been defined by its inert content and use in clinical trials. In recent years, several studies have demonstrated its effect in the treatment of major depression. The aim of this paper is to present the conclusions of recent meta-analyses of the placebo effect in major depression, to explain the mechanism by which placebo exerts its effect, and to discuss w...

BACKGROUND Double-blind, placebo-controlled (DBPC) trials are the gold standard for demonstrating clinical efficacy and tolerability. The placebo effect, although an important feature in placebo-controlled studies, has never been systematically investigated in allergen-specific immunotherapy (SIT) studies. This study was performed to examine the placebo response in SIT trials that employed a ba...

Placebo effects are beneficial health outcomes not related to the relatively direct biological effects of an intervention and can be elicited by an agent that, by itself, is inert. Understanding these placebo effects will help to improve clinical trial design, especially for interventions such as surgery, CNS-active drugs and behavioural interventions which are often non-blinded. A literature r...

conclusions dexamethasone 8mg is a better anti-emetic agent than metoclopramide for the prevention of post-operative nausea and vomiting after laparoscopic cholecystectomy. objectives this study evaluates the prophylactic anti-emetic effect of dexamethasone in comparison with metoclopramide and placebo for the prevention of post-operative nausea and vomiting in patients undergoing elective lapa...