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Placebos have been shown to produce significant positive changes in several health and mental health problems, referred to as placebo effects. Although it is well established that stimulant medication is an empirically supported treatment for children with attention-deficit hyperactivity disorder (ADHD), little is known about the role of placebos in the medication treatment of children with ADH...

BACKGROUND Antidepressants are often considered to be mere placebos despite the fact that meta-analyses are able to rank them. It follows that it should also be possible to rank different placebos, which are all made of sucrose. To explore this issue, which is rather more epistemological than clinical, we designed an unusual meta-analysis to investigate whether the effects of placebo in one sit...

PLACEBO EFFECTS IN MEDICINE1 For many years, the placebo response has been trivialized and even referred to as an “inert substance.” In a groundbreaking article recently published in The New England Journal of Medicine, Kaptchuk and Miller elucidate mechanisms underlying the placebo response and highlight findings to date regarding placebo effects. They note that placebo effects result from com...