Abstract: Objective: To determine the maternal & perinatal morbidity and mortality associated with Placenta Praevia in Bangladesh. To assess the risk factors of antepartum hemorrhage associated with Placenta Praevia. Design: A cross sectional observational hospital based descriptive study. Setting: Obstetric inpatient units of two tertiary care teaching hospitals of Dhaka. Participants: One hun...

Background and aim: Horseshoe placenta is a variant of ring-shaped placenta. Ring-shaped placenta is a rare anomaly seen in fewer than 1 in 6000 deliveries, which could be seen as horseshoe shape due to atrophy in a portion of the ring. This report refers to a possible relationship between the horseshoe shape placenta and preterm labor; although it has not been yet validated in the literature. ...

Context: Recently, a new coronavirus (SARS-CoV-2) as the cause of COVID-19 has made global health crisis and great challenge. Pregnant women fetuses are among high-risk groups for COVID-19. In this review, we summarize studies regarding SARS-CoV-2 virus-placenta interactions at maternal-fetal interface by demonstrating pathogenicity virus defense methods placenta. Evidence Acquisition: present ...

The integrase inhibitors elvitegravir (EVG) and dolutegravir (DTG) rapidly decrease the plasma HIV-1 viral load, a key factor in the prevention of maternal-to-fetal transmission of HIV-1. No data have been reported on the concentrations of these drugs in cord blood, maternal peripheral blood mononuclear cells (PBMCs), or placental tissue in pregnant women. We present in vivo pharmacokinetic dat...

the aim of current study was to determine women´s maternal asthma in pregnancy, delivery and birthl outcomes. using a retrospective cohort design, data of 580 pregnant women were gathered form a large teaching hospital in tehran, iran. the medical records of pregnant women who had attended this hospital between 2009 and 2011 were assessed. data of delivery and birth outcomes were gathered by ob...

The distribution of 14C-styrene was studied in the pregnant mouse using a whole body low temperature autoradiographic technique. In unsectioned tissues studied by liquid scintillation the concentrations of styrene and its metabolites in maternal and fetal blood and organs and in the placenta and amniotic fluid were determined. The organs which had higher concentrations of volatile styrene were ...

Growth and survival of the mammalian embryo within the uterine environment depends on the placenta, a highly complex vascularized organ comprised of both maternal and foetal tissues. Recent experiments demonstrate that the zinc finger transcriptional repressor Prdm1/Blimp1 is essential for specification of spiral artery trophoblast giant cells (SpA-TGCs) that invade and remodel maternal blood v...

There are two mechanisms by which the fetus escapes damage from the maternal immune response during pregnancy. First, the placenta serves as an antigen-bearing immunoabsorbent barrier between the maternal and fetal circulation, so that the mother's humoral immune response to fetal antigens derived from the paternal major histocompatibility complex has no effect on the fetus. Second, the placent...

Fetal brain hypoxic injury remains a concern in high-risk delivery. There is significant clinical interest in agents that may diminish neuronal damage during birth asphyxia, such as in allopurinol, an inhibitor of the prooxidant enzyme xanthine oxidase. Here, we established in a rodent model the capacity of allopurinol to be taken up by the mother, cross the placenta, rise to therapeutic levels...

Aim: Fetuin A is a multifunctional protein which marker of pathological calcification in several diseases. This study aimed to evaluate serum fetuin level term pregnancies with grade 3 placental calcification.
 Material and Method: Fifty-seven pregnant women who applied obstetrics outpatient clinic for routine pregnancy follow-up at were included this study. The was designed prospectively....