Background: Recent evidence has indicated that beta-secretase 1 (BACE1) is involved in the production of amyloid beta (Aβ) in patients affected with Alzheimer’s disease (AD). Therefore; the purpose of this study was to measure mRNA and plasma levels of BACE1 in AD patients, as an early diagnosis biomarker for such individuals. Methods: A total number of thirty AD patients and thirty normal sub...

The aim of the study is to assess the diagnostic accuracy of some fibrinolytic parameters in the differential diagnosis between patients with unstable angina (UA) and musculoskeletal disorders (MSD). Methods. This cross-sectional study included 119 patients with chest pain (CP) and provisional diagnosis “UA”. After a full set of diagnostic procedures, authors formed 4 groups: patients with isc...

An outpatient diagnostic procedure measuring the 6-hour integrated plasma concentration of aldosterone and plasma renin activity was used to detect primary aldosteronism in 12 patients with low renin hypertension, including six with mild hypertension and normal urinary excretion and spot plasma levels of aldosterone. The ratio of integrated plasma concentration of aldosterone to plasma renin ac...

MicroRNAs (miRNAs) have been frequently reported to be diagnostic biomarkers and prognostic factors for cancer. The aim of the present study was to evaluate the clinical significance of microRNA-139 (miRNA-139) in hepatocellular carcinoma (HCC). All 31 patients enrolled in the present study had received curative hepatectomy. The objective miRNA was determined using miRNA microarray. The miRNA-1...

The present study investigated the possible protective effect of Helicteres isora (Sterculiaceae) bark extracts on certain biochemical markers in streptozotocin (STZ)-induced diabetes in rats. STZ treatment (60 mg/kg/i.p) caused a hyperglycemic state that led to various physiological and biochemical alterations. Blood levels of glucose, urea, uric acid and creatinine, plasma levels of albumin a...

In this study, various diagnostic tools were constructed and plasma factors measured to evaluate the intelligence of process equipment. We used an ICP (Inductively Coupled Plasma) reactor with a radio frequency (RF) power 13.56 MHz, 400 800 W, pressure 10 30 mTorr. Plasma parameters such as electron density (ne), temperature (Te), potential (Vp), floating (Vf) using several instruments (VI prob...

the present study investigated the possible protective effect of helicteres isora (sterculiaceae) bark extracts on certain biochemical markers in streptozotocin (stz)-induced diabetes in rats. stz treatment (60 mg/kg/i.p) caused a hyperglycemic state that led to various physiological and biochemical alterations. blood levels of glucose, urea, uric acid and creatinine, plasma levels of albumin a...