Hinge motions are important for molecular recognition, and knowledge of their location can guide the sampling of protein conformations for docking. Predicting domains and intervening hinges is also important for identifying structurally self-determinate units and anticipating the influence of mutations on protein flexibility and stability. Here we present StoneHinge, a novel approach for predic...

Plastic surgery is a unique specialty that defies definition, has no organ system of its own, is based on principles rather than specific procedures, and, because of cosmetic surgery, is the darling of the media. What is plastic surgery? No complete definition exists. Joe McCarthy defines it as the “problem-solving specialty.” My wife, an anesthesiologist, calls plastic surgeons the “finishers”...

This paper briefly presents a gear joint with two degrees of freedom and describes possibility use for manipulators unmanned flying manipulators. A kinematic scheme is developed its characterizations. Its characterization expressed as function parameters external applied torques input speeds on the shaft. General schemes are considered manipulator design operation analysis joint.

Abstract Recently, hinge epistemologists have applied Wittgenstein’s metaphor of hinges to religious belief. The most prominent proposal in this context is Pritchard’s “quasi-fideism”. This paper examines some historical precursors the notion hinges, with aim shedding more light on it. After outlining framework epistemology and its application belief, I briefly examine views Thomas Reid John He...

Abstract In order to study the seismic behavior of bottom large-bay frame with different special-shaped columns, numerical models columns ordinary, dark and square at are established using finite element analysis in ANSYS. The three type Frame performed nonlinear time-history dynamic method under earthquakes. characteristics response RC conducted. weak parts development plastic hinges on end be...

The techniques used in the fabrication of micro-electro-mechanical systems (MEMS) were adopted from the integrated circuits (IC) industry and are mostly limited to patterning thin films on a flat substrate. As a consequence, micro-machined devices mostly comprise sets of flat two-dimensional (2D) membranes with etched patterns and undercuts that enable them to serve their intended functions. Ho...

To investigate the seismic behavior of end-plate connection semi-rigid space steel frames, three 1/4-scale specimens were tested under cyclic load. Finite element analysis which took initial geometric imperfections into consideration was also conducted, and the results conform to experimental results. The failure modes, hysteretic behavior, deformation capacity and energy-dissipation capacity o...