The plasticizer di(2-ethylhexyl)phthalate (DEHP) used in peritoneal dialysate bags is known to dissolve into the solution, even though the quantity is small. Long-term exposure of the peritoneum to DEHP could be a cause of peritoneal deterioration. Although some papers have been published about DEHP toxicity to the peritoneum, acute DEHP toxicity is not fully understood to date. We therefore co...

there has been a renewed interest in edible films made of renewable and natural polymers such as protein, polysaccharide and lipids. natural polymers derived from natural sources like food protein, offer the greatest opportunities because of their biodegradability and their ability to supplement nutritional value of foods. faba bean is a valuable source of protein and is cultivated in large qua...

The objective of this research work was to design, develop and optimize the self micro-emulsifying drug delivery system (SMEDDS) of Felodipine (FL) filled in hard gelatine capsule coated with polymer in order to achieve rapid drug release after a desired time lag in the management of hypertension. Microemulsion is composed of a FL, Lauroglycol FCC, Transcutol P and Cremophor EL. The optimum sur...

Thermoplastic sugar beet pulp (thermo-mechanical processing was discussed in previous studies) was formed into film strips by extrusion. Film tensile properties are discussed according to the molecular structure of external plasticizer. Sorbitol, fructose and adipic acid have a marked antiplasticizing effect, while urea and xylitol gave higher ultimate tensile stress than glycerol for a compara...

practically all important properties of the agricultural products, the foods and the biological objects. Among the properties, the important role is played bymechanical properties including the viscoelastic ones. These properties are influenced mainly by temperature and the strain rate but water plays the role of the main plasticizer in the controlling mechanisms. The relative simple models wer...

A renewable resource, epoxidized jatropha oil (EJO), was used as a green plasticizer and added to poly(lactic acid) (PLA). EJO was compounded into PLA at different contents. The addition of 3 wt % EJO to the PLA demonstrates significant improvement in flexibility, which leads to a percentage increase of about 7000% in elongation at break. This tensile result was confirmed by surface morphology ...

The aim of this work was to develop a pulsatile release system with metoprolol for chronotherapeutical use by coating swellable mini-tablets with Eudragit RS. To study the influence of the formulation factors (amount of coating polymer, plasticizer percentage in film coating and swelling agent percentage in mini-tablets), a Box-Behnken design of experiment (DoE) was used. To evaluate the influe...

A lipase from Thermomyces lanuginosus and cutinases from Thermobifida fusca and Fusarium solani hydrolysed poly(ethylene terephthalate) (PET) fabrics and films and bis(benzoyloxyethyl) terephthalate (3PET) endo-wise as shown by MALDI-Tof-MS, LC-UVD/MS, cationic dyeing and XPS analysis. Due to interfacial activation of the lipase in the presence of Triton X-100, a seven-fold increase of hydrolys...

The purpose of this research is to study the effect methods preliminary preparation thermally activated clay, which a pozzolanic component in water-resistant composite gypsum binders, as well mechanochemical activation joint grinding clay with addition plasticizer on activity and change required number composition binders. It was found that amount gypsum-cement-pozzolan when ground specific sur...

Antioxidant biocomposites have been successfully developed from cellulose acetate, eco-friendly triethyl citrate plasticizer and onion extract as a source of natural antioxidants. First, an onion extraction process was optimized to obtain the extract with highest antioxidant power. Extracts under absolute ethanol and ethanol 85% were the extracts with the highest antioxidant activity, which wer...