Tuberculosis (TB) is one of the oldest and commonest infectious diseases also known as “master of Death”. Pulmonary TB (PTB) and TB with pleural effusion remains a diagnostic challenge. Adenosine deaminase (ADA) is an enzyme of purine catabolism which is an inexpensive and easy test in early routine evaluation of patients with pleural effusion. Aim: To assess the diagnostic level of ADA in TB p...

Background: Fluids collect in the pleural space under different conditions and they are of different types. Detailed study of demographic attributes and aetiology of pleural collections has not been well reported in Africa. Aims and Objectives: This study was conducted to determine the demographic attributes and aetiology of common pleural space fluid collections. Methods: The sample population...

Thoracoscopy is currently the gold standard for the diagnosis and treatment of pleural diseases. Its diagnostic yield is 95% in patients with malignant pleural disease, with approximately 90% successful pleurodesis for malignant pleural effusion and 95% for pneumothorax. At the same time, thoracoscopy constitutes an important tool in the research of pleural pathophysiology and molecular biology...

Classically described; pleural effusion is the accumulation of fluid in the pleural gap that may be caused by any reason [4]. If there is an evidence of invasion by the tumor or any malignant cells detected in this fluid, it is described as malignant pleural effusion. Although there has been no epidemiologic study with respect to pleural effusion yet, it is a common clinic problem which is esti...

UNLABELLED Malignant mesothelioma is doubtless the more known pleural tumour. However, according to the morphology code of the International Classification of Diseases for Oncology (ICD-O), there are several histological types of pleural neoplasms, divided into mesothelial, mesenchymal and lymphoproliferative tumours, that may be misdiagnosed. In this paper we summarise and illustrate the incid...

Over the past 10 years, the widespread clinical applicability of semi-invasive and noninvasive diagnostic tools including medical thoracoscopy and ultrasonography has expanded the occurrence of pleural effusions to include several rare diseases such as granulomatous, connective tissue and autoimmune disorders including sarcoidosis, granulomatosis with polyangiitis (Wegener's), systemic sclerosi...

Our knowledge of the cell types from normal pleural fluid of laboratory animals forms the basis of our experimental investigation of the inflammatory diseases of the pleura in humans. We sought to standardise the various cell numbers in normal pleural fluid of rabbits as well as assess the use and power of aspiration and pleural lavage as experimental tools. Fluid from the left and right pleura...

As an aid in the differential diagnosis of exudative pleural effusions, tumor markers were investigated. We measured immunosuppressive acidic protein (IAP), carbohydrate antigen 19-9 (CA 19-9), tissue polypeptide antigen (TPA), carcinoembryonic antigen (CEA), adenosine deaminase (ADA), and alpha 1-acid glycoprotein (AGP) in the pleural fluid of 36 patients with carcinomatous pleural effusions a...