Abstract For the use of polymers as biomaterials in production implants, several processing methods are needed. Besides injection molding or Fused Deposition Modeling temperature based processes, also solvent processes were performed such solvent-casting and electrospinning. As fabrication medical devices makes potentially hazardous toxic solvents, they have to be extracted from final device. a...

Bast fibers from stems of kenaf (Hibiscus cannabinus, L.), a warm-season tropical herbaceous annual plant, were dispersed into poly-L-lactide (PLLA) matrix by melt-mixing followed by compression molding. Low fiber fractions (1–5%) were investigated. The composites showed a slight lowering of thermal stability when evaluated by thermogravimentric analysis. X-ray diffraction and differential scan...

PURPOSE: The current gold standard for the repair of segmental bone defects is autologous bone grafts or flaps, however these are limited by donor site morbidity, limited graft tissue availability, and potential for complications at the harvest site. ASCs (adipose derived stem cells) have potential to aid bone regeneration due to their ability to differentiate into osteoblasts. BMP-2 (bone morp...

Currently, cell culture systems that include nanoscale topography are widely used in order to provide cells additional cues closer to the in vivo environment, seeking to mimic the natural extracellular matrix. Electrospinning is one of the most common techniques to produce nanofiber mats. However, since many sensitive parameters play an important role in the process, a lack of reproducibility i...

PURPOSE: The current gold standard for the repair of segmental bone defects is autologous bone grafts or flaps, however these are limited by donor site morbidity, limited graft tissue availability, and potential for complications at the harvest site. ASCs (adipose derived stem cells) have potential to aid bone regeneration due to their ability to differentiate into osteoblasts. BMP-2 (bone morp...

Hybrid materials constituted by peptides and synthetic polymers have nowadays a great interest since they can combine the properties and functions of each constitutive block, being also possible to modify the final characteristics by using different topologies. Poly(l-lactide-b-l-phenylalanine) copolymers with various block lengths were synthesized by sequential ring-opening polymerization of l...

Biodegradable fibers of poly(L-lactic acid) (PLLA) and poly(D,L-lactide-co-glycolide) (PLGA) that encapsulated a water-soluble drug were created by a patented technique consisting of wet-spinning a water-in-oil emulsion. These fibers are 2.4% by mass drug, which is slowly released, making these fibers potential candidates for implantation as drug delivery devices and/or tissue-engineering subst...

Thermal decomposition behavior of Poly(L-lactic acid) (PLLA) and PLLA composites after different heat treatment were investigated using thermogravimetric analysis. Firstly, the thermal decomposition results of neat PLLA showed that the decomposition of PLLA was a first-order kinetic reaction, and thermal decomposition kinetics indicated that the heat treatment significantly affected activation ...

Metal halide perovskites (MHPs) based phosphor-converted light-emitting diodes (pc-LEDs) are limited by the low MHP stability under storage/operation conditions. A few works have recently stablished in-situ synthesis of MHPs into polymer matrices as an effective strategy to enhance with a low-cost fabrication. However, this is within petrochemical-based polymers. Herein, first ambient preparati...

In this study, L-lactide was used to modify the tricalcium phosphate (β-TCP) and tetracalcium phosphate (TTCP) surface which can form functionalized poly(l-lactic acid) (PLLA)-grafted β-TCP (g-β-TCP) and PLLA-grafted TTCP (g-TTCP) particles. The g-β-TCP and g-TTCP obtained were incorporated into a PEG-PCL-PEG (PECE) matrix to prepare injectable thermosensitive hydrogel composites. The morpholog...