نتایج جستجو برای: poly 2
تعداد نتایج: 2586515 فیلتر نتایج به سال:
Cationic polymers obtained via partial reduction of poly(2-ethy-2-oxazoline)s were studied on their cytocompatibility and buffer capacity in acidic environment.
Background: Polyinosinic:polycytidylic acid (Poly-IC) has been used as a viral stimulus to mimic in vivo and in vitro infection induced by some viruses. Objective: To determine whether non-viable Lactobacillus casei CRL431 (LcM) can modulate the immune response induced by Poly I:C in co-culture models of peripheral blood mononuclear cells (PBMC) and A549 cells. Methods: T and NK cell activati...
We have performed a phase IB study of polyinosinic-polycytidylic acid complexed with poly-L-lysine and carboxymethylcellulose (poly-ICLC) in combination with interleukin 2 (IL-2) in 25 patients with a variety of cancers. Patients received weekly or biweekly poly-ICLC by i.m. injection, at doses ranging from 0.01 to 1.0 mg/m2, for 1 month. This was followed by 2 months of outpatient therapy with...
The incorporation of an amino group into a bifunctional initiator for the cationic ring-opening polymerization (CROP) is achieved in two-step reaction. Detailed kinetic studies using 2-ethyl-2-oxazoline demonstrate initiators' eligibility CROP yielding well-defined polymers featuring molar masses about 2000 g mol-1 . Deprotection phthalimide moiety subsequent to enables introduction cyclooctyne...
Here we report on the preparation of well defined water-soluble poly(2-methyl-2-oxazoline) and poly(2-ethyl-2-oxazoline) terminally equipped with a chelator (N,N',N'',N'''-tetraazacylododecane-1,4,7,10-tetraacetic acid (DOTA)) for radionuclide labeling. The tissue distribution and excretion of (111)In-labeled poly(2-alkyl-2-oxazoline)s were studied in mice. We found that the hydrophilic polymer...
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