نتایج جستجو برای: poly lactic co glycolic acid

تعداد نتایج: 1112507  

Curcumin has been found to be very efficacious against many different types of diseases. However, the major disadvantage associated with the use of curcumin is its low systemic bioavailability. In the present study the protective effects of curcumin-loaded poly lactic-co-glycolic acid nanoparticles (nanocurcumin) against mono-iodoacetate-induced osteoarthritis in rats was inves...

2017
Yongchao Chu Ning Chen Huajun Yu Hongjie Mu Bin He Hongchen Hua Aiping Wang Kaoxiang Sun

A nanoparticle (NP) was developed to target choroidal neovascularization (CNV) via topical ocular administration. The NPs were prepared through conjugation of internalizing arginine-glycine-aspartic acid RGD (iRGD; Ac-CCRGDKGPDC) and transactivated transcription (TAT) (RKKRRQRRRC) peptide to polymerized ethylene glycol and lactic-co-glycolic acid. The iRGD sequence can specifically bind with in...

Journal: :Tissue engineering. Part A 2011
Katsuhiro Takeda Noriyuki Sakai Hideki Shiba Takayoshi Nagahara Tsuyoshi Fujita Mikihito Kajiya Tomoyuki Iwata Shinji Matsuda Kazuko Kawahara Hiroyuki Kawaguchi Hidemi Kurihara

Brain-derived neurotrophic factor (BDNF), for which bovine collagen-derived atelocollagen is used as a scaffold, enhances periodontal tissue regeneration. However, a scaffold that does not contain unknown ingredients is preferable. Since the synthesized high-molecular-weight (HMW)-hyaluronic acid (HA) is safe and inexpensive, we evaluated the efficacy of HMW-HA as a BDNF scaffold. CD44, a major...

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