A fifty four years old male was followed in nephrology clinic since 1999 for hepatorenal polycystic disease. The patient was referred for abdominal distension with postprandial fullness. Family history of hepatorenal polycystic disease in the father, grandmother and a paternal aunt. On physical examination there was a globular abdomen, with multiple irregular masses, which imprint on the abdomi...

BACKGROUND Spontaneous coronary artery dissection is an uncommon syndrome. Its prevalence among patients with polycystic kidney disease is very rare, with no previously reported involvement of the right posterior descending coronary artery. CASE PRESENTATION We describe the case of a middle-aged Caucasian woman with polycystic kidney disease who presented with a non-ST elevation myocardial in...

Polycystic ovary syndrome (PCOS) is a heterogeneous endocrine disorder with variable prevalence, affecting about one in every 15 women worldwide. The diagnosis of polycystic ovary syndrome requires at least two of the following criteria: oligoovulation and/or anovulation, clinical and/or biochemical evidence of hyperandrogenism and morphology of polycystic ovaries. Women with PCOS appear to hav...

Polycystic ovarian syndrome (PCOS) is the most common form of chronic anovulation associated with androgen excess. Large scale studies have observed a prevalence rate of PCOS 5% to 10% among reproductive-age women.1,2 Currently, there are 3 widely accepted sets of criteria for diagnosis of PCOS.3,4 After excluding other causes of hyperandrogenism, National Institute of Health (NIH) criteria (19...

The purpose of this paper is to provide a stepwise approach to treating the infertility/subfertility associated with polycystic ovary syndrome. Defining polycystic ovary syndrome in a patient requires first investigating other possible causes for polycystic ovary morphology, acne, hirsutism, obesity, and the metabolic derangements that often accompany polycystic ovary syndrome. Beginning with l...

This study aimed to detect the levels of matrix metalloproteinases (MMP)-2 and -9, using enzyme-linked immunosorbent assays, in the follicular fluid of 35 patients with polycystic ovaries, compare them with the levels found in 35 normally ovulating women enrolled in their first in vitro fertilization (IVF) cycle and then correlate them with pregnancy rates in these two groups. Levels of MMP-9 w...

PCOS, features and diagnosis Polycystic ovary syndrome (PCOS) is a common reproductive endocrinological disorder among women of fertile age. The history of PCOS dates back to 1721. Sclerocystic changes were pointed out in the human ovary as early as 1844. However, the disorder was first described in 1935 by Stien & Leventhal in women who presented with amenorrhea, infertility and bilateral enla...

Primary cilia are nonmotile, microtubule-based, antenna-like organelles projecting from the apical surface of most mammalian cells. Elegant studies have established the importance of ciliary structure and function in signal transduction and the sensory roles of cilia in maintaining healthy cellular state. In particular, dysfunctional cilia have been implicated in a large number of diseases main...

BACKGROUND Non-total liver resecting invasive treatment of polycystic liver disease has different recurrence rates. The aim of this study is to illustrate why the recurrence rates are different. We established a hypothesis that the cyst number is a constant in polycystic liver disease in a patient's lifetime. MATERIAL AND METHODS We selected 287 patients with polycystic liver, in which 35 pat...

Autosomal-dominant polycystic kidney disease is frequently complicated by polycystic liver disease. Some patients with polycystic liver disease have a full-stomach sensation and intractable ascites. We report a 56-year-old woman with polycystic liver disease waiting to receive a liver transplant, with a chief complaint of a full-stomach sensation and refractory ascites, wherein the transcathete...