Polylactic acid (PLA) fiber, also known as corn fiber, is made of corn and other grains through fermentation, polymerization and spinning. Thus it is biodegradable and environmentally friendly. Three kinds of buffer solutions with PH values of 4, 7.2 and 11 were made for the investigation of the degradation properties of PLA. The experimental results showed that the degradation of polylactic ac...

Poly(3-hydroxybutyrate-co-3-hydroxyvalerate) and poly(3-hydroxybutyrate-co-3-hydroxyhexanoate) were used to prepare microbeads, with diameter ranging from 50 100 µm, by an emulsion-evaporation process. The emulsification-evaporation process enables the formation of spherical polyhydroxyalcanoate beads, crystalline rates similar ones former polymer important surface roughness as compared amorpho...

The hepatitis C virus (HCV) is an infection that affects the liver tissues in humans, leading to the development of effective prophylactic and therapeutic HCV vaccines to prevent a global epidemic. Scientists consider it challenging to produce a therapeutic vaccine for the treatment of hepatocellular carcinoma as opposed to a preventative vaccine. However, several drawbacks are involved with a ...

Abstract We compared the performance of bio-based and biodegradable polymers for packaging applications. Cost-effective inorganic fillers (talc, kaolin calcium carbonate) were first melt-compounded with polylactic acid (PLA), poly(butylene adipate-co-terephthalate) (PBAT) poly(hydroxy butyrate-co-valerate) (PHBV). Following this, injection- compression-molded specimens produced to test effect f...

Lactic acid production by fermentation has attracted interest because optically pure lactic acid is the raw material of biodegradable polymer, polylactic acid, which has been mainly used in food packing. In situ extractive fermentation of lactic acid with reactive extraction has two critical problems: the toxicity of diluents and extractant and the difference in the optimum pH between fermentat...

Aims: To investigate the potential of curcumin-loaded polylactic-co-glycolic acid nanoparticles (CUR-PLGA-NPs), alone and with electrostatic precipitation, for improving tissue uptake during pressurized intraperitoneal aerosol chemotherapy (PIPAC). Methods: Positively negatively charged CUR-PLGA-NPs were delivered as PIPAC into inverted bovine urinary bladders ex vivo. The experiment was repeat...

Background: Drug nano-carriers are one of the most important tools for targeted cancer therapy so that undesired side effects of chemotherapy drugs are minimized. In this area, the use of ultrasound can be helpful in controlling drug release from nanoparticles to achieve higher treatment efficiency.Objective: Here, we studies the effects of ultrasound irradiation on the release profile of 5-flu...

  Objective: In dental treatments, use of carriers for targeted antibiotic delivery would be optimal to efficiently decrease microbial count. In this study, gentamicin was loaded into polylactic co-glycolic acid (PLGA) microspheres and its release pattern was evaluated for 20 days.   Methods: In this experimental study, PLGA microspheres loaded with gentamycin were produced by the W/O/W method....