Self-assembled monolayers and bulk films of thioanilines, polymerized on gold and platinum surfaces, have been characterized and compared to bulk polyaniline (PANI) films. In a previous study [Kuwabata; et al. Langmuir 1999, 15, 6807-6812], only one redox couple was observed in the cyclic voltammetric profile of a polymerized monolayer of thioaniline on gold, in contrast to the known profiles o...

The microtubule-depolymerizing drug, vincristine, is effective in the treatment of acute lymphoblastic leukemia (ALL). Although vincristine resistance mechanisms have been extensively characterized in cell lines, their clinical relevance is poorly understood. The aim of the current study was to define clinically relevant mechanisms of vincristine resistance in a panel of childhood ALL xenograft...

The degradation of high molecular weight as-polymerized poly(L-lactide) (PLLA) is very slow; it takes more than 5.6 yr for total resorption. Moreover, the degradation products of as-polymerized PLLA bone plates, consisting of numerous stable particles of high crystallinity, are related with a subcutaneous swelling in patients 3yr postoperatively. In order to avoid these complications, polymers ...

Previously, we have shown that galaptin, an endogenous ß-galactosidebinding lectin, is present in extracellular matrix where it may participate in the adhesion of AI21 human ovarian carcinoma cells to extracellular matrix via interaction with specific cell surface carbohydrate receptors. We now report that A121 cells adhere to polystyrene plates coated with polymerized human splenic galaptin. ...

Polymerizable liquid crystalline semiconductors, referred to as reactive mesogens RMs , consist of -conjugated cores with reactive end groups decoupled by an aliphatic spacer. These can be polymerized within the mesophase, maintaining the self-assembled morphology and charge transport characteristics. The polymerized films can then be used in organic electronic applications such as charge trans...