نتایج جستجو برای: polymicrobial infection

تعداد نتایج: 457440  

Journal: :Infection and immunity 2001
I Celik C Stover M Botto S Thiel S Tzima D Künkel M Walport W Lorenz W Schwaeble

The complement system and the natural antibody repertoire provide a critical first-line defense against infection. The binding of natural antibodies to microbial surfaces opsonizes invading microorganisms and activates complement via the classical pathway. Both defense systems cooperate within the innate immune response. We studied the role of the complement system in the host defense against e...

Journal: :Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 1998
J H Wang Y C Liu S S Lee M Y Yen Y S Chen J H Wang S R Wann H H Lin

Pyogenic liver abscess is an uncommon complication of intra-abdominal or biliary tract infection and is usually a polymicrobial infection associated with high mortality and high rates of relapse. However, over the past 15 years, we have observed a new clinical syndrome in Taiwan: liver abscesses caused by a single microorganism, Klebsiella pneumoniae. We reviewed 182 cases of pyogenic liver abs...

Journal: :Journal of immunology 2015
James L Wynn Philip O Scumpia Blair T Stocks Joann Romano-Keeler Mhd Wael Alrifai Jin-Hua Liu Annette S Kim Catherine E Alford Pranathi Matta Jörn-Hendrik Weitkamp Daniel J Moore

Sepsis is a major cause of neonatal mortality and morbidity worldwide. A recent report suggested that murine neonatal host defense against infection could be compromised by immunosuppressive CD71(+) erythroid splenocytes. We examined the impact of CD71(+) erythroid splenocytes on murine neonatal mortality to endotoxin challenge or polymicrobial sepsis and characterized circulating CD71(+) eryth...

Journal: :Journal of immunology 2011
Matthew J Delano Kindra M Kelly-Scumpia Terri C Thayer Robert D Winfield Philip O Scumpia Alex G Cuenca Phillips B Harrington Kerri A O'Malley Elizabeth Warner Sonia Gabrilovich Clayton E Mathews Drake Laface Paul G Heyworth Reuben Ramphal Robert M Strieter Lyle L Moldawer Philip A Efron

Neutrophils are essential for successful host eradication of bacterial pathogens and for survival to polymicrobial sepsis. During inflammation, the bone marrow provides a large reserve of neutrophils that are released into the peripheral circulation where they traverse to sites of infection. Although neutrophils are essential for survival, few studies have investigated the mechanisms responsibl...

2010
Brian M Peters Mary Ann Jabra-Rizk Mark A Scheper Jeff G Leid John William Costerton Mark E Shirtliff

The fungal species Candida albicans and the bacterial species Staphylococcus aureus are responsible for a majority of hospital-acquired infections and often coinfect critically ill patients as complicating polymicrobial biofilms. To investigate biofilm structure during polymicrobial growth, dual-species biofilms were imaged with confocal scanning laser microscopy. Analyses revealed a unique bio...

2009
A Freitas

Sepsis is a systemic inflammatory response resulting from the inability of the host to contain the infection locally. Previously, we demonstrated that during severe sepsis there is a marked failure of neutrophil migration to the infection site, which contributes to dissemination of infection, resulting in high mortality. IL-17 plays an important role in neutrophil recruitment. Herein, we invest...

Journal: :Journal of Dairy Science 2021

Digital dermatitis is a bacterial infection that causes lesions above the heel bulbs on cattle hooves, and several species from genus Treponema are suspected to be causative agents of this polymicrobial condition. Transmission bacteria healthy cows understudied, particularly with regard potential insect vectors. Therefore, objective research was determine if flies captured dairy farm known have...

Journal: :Journal of clinical microbiology 2014
Yaniv Keren Doron Keshet Mark Eidelman Yuval Geffen Ayelet Raz-Pasteur Khetam Hussein

Leclercia adecarboxylata infection is rarely reported in the context of human infections. In the scant cases reported in the literature, it usually involves individuals who are immunocompromised with infections of a polymicrobial nature. Recently, data have begun to accumulate suggesting that L. adecarboxylata is a pathogen associated with water environments. We review the literature regarding ...

Journal: :Antimicrobial agents and chemotherapy 2013
Amira A Bhalodi Jared L Crandon Gregory Williams David P Nicolau

Although Gram-positive cocci are the most common pathogens in diabetic foot infections, these infections often are polymicrobial. The objective of this study was to assess the efficacy of a simulated human dose of 600 mg ceftaroline fosamil-600 mg avibactam every 8 h as a 1-h infusion in a polymicrobial in vivo murine model. Seven isolates were used (3 methicillin-resistant Staphylococcus aureu...

Alireza Fatemi, Mohammad Afshin Alizadeh, Davood Yadegarynia, Masih Mahdizadeh, Reihaneh Kabiri Movahhed,

Background: Neutropenic patients are vulnerable to a wide spectrum of infectious agents. The aim of this study was to determine the current frequency of bacterial infections in patients with nosocomial fever and neutropenia. Methods: In a retrospective study, the neutropenic patients’ specimens with nosocomial fever were cultured on blood and MacConkey agar plates and evaluated at microbiology ...

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