Anti-vaccine sentiment found fertile soil in the US, where the ethos of individual responsibility often clashed with public health programs based on collective norms. As Allen notes, Americans remained suspicious of calls for mandatory vaccination. What kept vaccine opponents on the defensive, however, were the rapid breakthroughs in medicine and public health. Jenner's triumph was followed by ...

The lesions found in animals with epidemic rabbit pox have been described in this paper. The most distinctive gross lesion in all organs and tissues was the small nodule or papule which was found to consist of mononuclear infiltration and necrosis. Diffuse lesions were also found in which the infiltration was widespread and accompanied by edema, hemorrhage and extensive necrosis of affected tis...

Observations on an epidemic of rabbit pox occurring in an isolated animal room during the winter of 1933-34 are reported. The clinical manifestations, consisting of a generalized papular eruption involving the skin and mucous membranes, together with blepharitis, ophthalmia, nasal discharge and lymphadenopathy were essentially similar to those noted in a pox epidemic of the previous year. This ...

In addition to glycolysis, the oncogenic transcription factor c-MYC (MYC) stimulates glutamine catabolism to fuel growth and proliferation of cancer cells through up-regulating glutaminase (GLS). Glutamine is converted to glutamate by GLS, entering the tricarboxylic acid cycle as an important energy source. Less well-recognized, glutamate can also be converted to proline through Δ(1)-pyrroline-...

ing from consequences which were virtually certain to arrive, sooner or later. The exigencies of monthly publication preclude us from quoting figures which vary from day to day, and it must be enough to say that the number of cases at Gloucester Avhich have been diagnosed as small-pox has been so large that the utmost anxiety is reasonably felt as to when, and where, the epidemic will end. Thes...

Aim: To detect and differentiate Capripox virus (sheeppox virus and goatpox virus) infections by using 30 kDa RNA polymerase subunit (RPO30) gene based PCR. Materials and Methods: Two capripox viruses' viz., sheep pox virus (SPPV) and goatpox virus (GTPV) from clinical samples of different outbreaks were detected and differentiated using capri pox virus (CaPVs) genotyping PCR targeting the CaPV...

The aim of the study was to find out the host specificity of pigeon pox virus-1 (PPV-1) and fowl pox virus-2 (FPV-2) following cross infection with field strains from Bangladesh. The cross infection was investigated in five groups (n=5) of pigeons and seven groups of chickens (n=5) four weeks of age. Irrespective of route of inoculation each bird received either 0.1 mL of PPV-1 or FPV-2 having ...

Outbreak of sheep pox was noticed in flocks of Khilakaraisal in an organized government farm of Tirunelveli district during 2013. Mortality and morbidity rates were 4.17% and 80.00%, respectively. Both the sexes of sheep between 6 months to 2 years old were affected. DNA extracted from the scab specimens (n=5) were amplified using Capri pox specific p32 gene primers and yielded 192 bp product. ...

We have dissected the entire cis-regulatory region of the Drosophila Pox neuro gene with regard to its enhancers, and have analyzed their functions by the selective addition to Pox neuro null mutant flies of one or several functions, each regulated by a complete or partial enhancer. We have identified at least 15 enhancers with an astounding complexity in arrangement and substructure that regul...