نتایج جستجو برای: pp2581 2596

تعداد نتایج: 122  

Journal: :Environmental toxicology and chemistry 2016
Jiahua Guo Katherine Selby Alistair B A Boxall

The occurrence of antibiotic residues in the aquatic environment is an emerging concern. In contrast to daphnia and fish, algae are known to be particularly sensitive to antibiotic exposure. However, to date, a systematic evaluation of the sensitivity of different algal species to antibiotics has not been performed. The aim of the present study was therefore to explore the sensitivity of a batt...

Journal: :The Journal of endocrinology 2001
S Siffroi-Fernandez F Delom M C Nlend J Lanet J L Franc A Giraud

Thyroglobulin (Tg) binds to cell surfaces through various binding sites of high, moderate and low affinity. We have previously shown that binding with low to moderate affinity is pH dependent, selective, but not tissue specific. To identify the regions of Tg involved in this cell surface binding, we studied the binding of (125)I-labeled cyanogen bromide peptides from human Tg to cell surfaces o...

2009
Nan Chen Weiming Wang Yanping Huang Pingyan Shen Daoling Pei Haijin Yu Hao Shi Qianying Zhang Jing Xu Yilun Lv Qishi Fan

BACKGROUND The study was performed to investigate the prevalence, awareness and the risk factors of chronic kidney disease (CKD) in the community population in Shanghai, China. METHODS A total of 2596 residents were randomly recruited from the community population in Shanghai, China. All were screened for albuminuria, haematuria, morning spot urine albumin-to-creatinine ratio and renal functi...

Journal: :Health policy 2006
Friedrich Breyer Stefan Felder

Some people believe that the impact of population ageing on future health care expenditures will be quite moderate due to the high costs of dying. If not age per se but proximity to death determines the bulk of expenditures, a shift in the mortality risk to higher ages will not affect lifetime health care expenditures as death occurs only once in every life. We attempt to take this effect into ...

2014
Sun Ha Jee Yangsoo Jang Dong Joo Oh Byung-Hee Oh Sang Hoon Lee Seong-Wook Park Ki-Bae Seung Yejin Mok Keum Ji Jung Heejin Kimm Young Duk Yun Soo Jin Baek Duk Chul Lee Sung Hee Choi Moon Jong Kim Jidong Sung BeLong Cho Eung Soo Kim Byung-Yeon Yu Tae-Yong Lee Jong Sung Kim Yong-Jin Lee Jang-Kyun Oh Sung Hi Kim Jong-Ku Park Sang Baek Koh Sat Byul Park Soon Young Lee Cheol-In Yoo Moon Chan Kim Hong-Kyu Kim Joo-sung Park Hyeon Chang Kim Gyu Jang Lee Mark Woodward

OBJECTIVE The objectives of this study were to develop a coronary heart disease (CHD) risk model among the Korean Heart Study (KHS) population and compare it with the Framingham CHD risk score. DESIGN A prospective cohort study within a national insurance system. SETTING 18 health promotion centres nationwide between 1996 and 2001 in Korea. PARTICIPANTS 268 315 Koreans between the ages of...

2002
Sylvie Côté Angelika Rosenauer Andrea Bianchini Karen Seiter Jonathan Vandewiele Clara Nervi

Resistance to all-trans retinoic acid (ATRA) remains a clinical problem in the treatment of acute promyelocytic leukemia (APL) and provides a model for the development of novel therapies. Molecular alterations in the ligand-binding domain (LBD) of the PML/RAR fusion gene that characterizes APL constitute one mechanism of acquired resistance to ATRA. We identified missense mutations in PML/RAR f...

2016
Noa G. Holtzman Vu Duong Nader Hanna Howard M. Richard Ashkan Emadi

Transfusion-refractory thrombocytopenia is an important clinical challenge in the treatment of patients with myelodysplastic syndrome. Hypersplenism can play a major role in splenic platelet sequestration and transfusion refractoriness, and though rare in myelodysplastic syndrome, it can commonly be seen in a wide range of other benign and malignant conditions. Splenectomy has been an effective...

2013
Katie Harron Harvey Goldstein Angie Wade Berit Muller-Pebody Roger Parslow Ruth Gilbert

BACKGROUND Linkage of risk-factor data for blood-stream infection (BSI) in paediatric intensive care (PICU) with bacteraemia surveillance data to monitor risk-adjusted infection rates in PICU is complicated by a lack of unique identifiers and under-ascertainment in the national surveillance system. We linked, evaluated and performed preliminary analyses on these data to provide a practical guid...

Journal: :Remote Sensing 2012
Lahiru S. Wijedasa Sean Sloan Dimitrios G. Michelakis Gopalasamy R. Clements

Landsat can be used to map tropical forest cover at 15–60 m resolution, which is helpful for detecting small but important perturbations in increasingly fragmented forests. However, among the remaining Landsat satellites, Landsat-5 no longer has global coverage and, since 2003, a mechanical fault in the Scan-Line Corrector (SLC-Off) of the Landsat-7 satellite resulted in a 22–25% data loss in e...

Journal: :Journal of biomechanical engineering 2010
Eunjung Kim Farshid Guilak Mansoor A Haider

The pericellular matrix (PCM) is the narrow tissue region surrounding all chondrocytes in articular cartilage and, together, the chondrocyte(s) and surrounding PCM have been termed the chondron. Previous theoretical and experimental studies suggest that the structure and properties of the PCM significantly influence the biomechanical environment at the microscopic scale of the chondrocytes with...

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