Gallaphosphen L(Cl)GaPGaL 1 (L=HC[C(Me)N(2,6-i-Pr2C6H3)]2) reagiert mit Carbodiimiden [C(NR)2; R=i-Pr, Cy] und Isocyanaten [RNCO; R=Et, i-Pr, unter [2+2]-Cycloaddition zu den viergliedrigen Metallaheterocyclen LGa(Cl)P[?-C(X)NR]GaL (X=NR, R=i-Pr 2, Cy 3; X=O, R=Et 4, i-Pr 5, 6). Verbindungen 4–6 reagieren CO2 reversibel bei Raumtemperatur sechsgliedrigen LGa(Cl)P[?-C(O)O]-?-C(O)N(R)GaL (R=Et 7,...

We explore three results related to hardness of counting. Interestingly, at their core each of these results relies on a simple — yet powerful — technique due to Valiant and Vazirani. Does SAT become any easier if we are guaranteed that the formula we are given has at most one solution? Alternately, if we are guaranteed that a given boolean formula has a unique solution does it become any easie...

Probabilistic OWL (PR-OWL) improves the Web Ontology Language (OWL) with the ability to treat uncertainty using Multi-Entity Bayesian Networks (MEBN). PR-OWL 2 presents a better integration with OWL and its underlying logic, allowing the creation of ontologies with probabilistic and deterministic parts. However, there are scalability problems since PR-OWL 2 is built upon OWL 2 DL which is a ver...

Treatment of Ni(NCS)2(PMe2Ph)2 with organic isocyanides CN-R gave five-coordinate isocyanide Ni(II) complexes, Ni(CN-R)(NCS)2(PMe2Ph)2 (R = C6H3-2,6-Me2 (1), t-Bu (2)). Interestingly, the corresponding reaction of Ni(NCS)2(P(n-Pr)3)2 with 2 equiv. of CN-t-Bu gave an unusual compound, which exists as an ion pair of the trigonal bipyramidal cation [Ni(P(n-Pr)3)2(CN-t-Bu)3]2+ (3) and the dinuclear...

background and objectives: the most prevalent malignancy among women is known to be breast cancer (bc). several factors contribute to determining tumor prognosis and treatment strategies. in this study, the frequency and relevance of these factors are discussed. materials and methods: this cross-sectional study was carried out on 214 patients with bc, who referred to the cancer institute of im...

PR-104, the phosphate ester of a dinitrobenzamide mustard [PR-104A; 2-((2-bromoethyl)-2-{[(2-hydroxyethyl) amino] carbonyl}-4,6-dinitroanilino)ethyl methanesulfonate], is currently in clinical trial as a hypoxia- and aldo-keto reductase 1C3 (AKR1C3)-activated prodrug for cancer therapy. Here, we investigate species (human, dog, rat, mouse) differences in metabolism to the corresponding O-glucur...

Reaction of d(0) Zr(NMe2)2[MeC(N(i)Pr)2]2 (1) with O2 at -30 °C gives three Zr containing products: a peroxo trimer {(μ-η(2):η(2)-O2)Zr[MeC(N(i)Pr)2]2}3 (2), an oxo dimer {(μ-O)Zr[MeC(N(i)Pr)2]2}2 (3), and an oxo polymer {(μ-O)Zr[MeC(N(i)Pr)2]2}n (4). is a rarely observed peroxo complex from the reaction of a d(0) complex with O2.

A Proofs of the theorems We first state a few helper lemmas. Lemma 1. Suppose the graph G is an (l, r)-regular graph, i.e. worker degree is l and task degree is r. Then, for each (w i , t j) 2 G, the following is true Pr(w i (t j) = 1) = 1 + (2 1)µ 2 , Pr(w i (t j) = 1) = 1 (2 1)µ 2 , and E[d + j ] = r 1 + (2 1)µ 2 , E[d j ] = r 1 (2 1)µ 2 where the probability and expectation are taken over th...

Estrogens act in brain to profoundly influence neurogenesis, sexual differentiation, neuroprotection, cognition, energy homeostasis, and female reproductive behavior and physiology through a variety of mechanisms, including the induction of progestin receptors (PRs). PRs are expressed as two isoforms, PR-A and PR-B, that have distinct functions in physiology and behavior. Because these PR isofo...