BACKGROUND The present study was undertaken to estimate and compare the levels of plasma total cholesterol (TC), low density lipoprotein (LDL), high density lipoprotein (HDL), very low density lipoprotein (VLDL) and triglycerides in patients with oral precancerous lesions/conditions, oral cancer and normal subjects. MATERIALS AND METHODS The study comprised of 60 patients with oral precancero...

Clinical research of gastrointestinal precancerous lesions is a key point in primary preven‐ tion of gastrointestinal cancer. It’s a long time from superficial gastritis to atrophic gastri‐ tis and to the gastric carcinoma finally. So how to effectively carry on the long-term followup of the gastric precancerous lesions becomes a perplexing medical problem [8; 2; 3; 7]. The most accurate ways t...

B3 lesions represent 3–10% of the histologically assessed lesions in mammography screening. They comprise different histopathological entities which provide benign histology, but are either known to show heterogeneity or to have an increased (albeit low) risk of associated malignancy, e.g. FEA, ADH, lobular neoplasia (LN), papillary lesions, radial scar, and phyllodes tumor. With regard to the ...

OBJECTIVE The identification of precancerous lesions is the basis of an early diagnosis, and of a treatment that allows, in the great part of cases, the preservation of organ functions. The aims of this study were: the evaluation of the less invasive treatment for precancerous lesion of the larynx to minimize the recurrences, the estimation of number of further operation required. METHODS A p...

Intestinal microecology refers to the interaction between host and microorganisms in human intestinal tract, which is composed mainly of flora. microflora affects physiological pathological changes through metabolic activity interaction. Precancerous lesion liver a potential benign disease, may lead malignant transformation liver. It intermediate stage from transformation. Recent studies have s...

PURPOSE It is important to identify the definitive molecular switches involved in the malignant transformation of premalignant tissues. Cellular senescence is a specific characteristic of precancerous tissues, but not of cancers, which might reflect tumorigenesis-protecting mechanisms in premalignant lesions. Polycomb protein Bmi1, which is a potent negative regulator of the p16INK4 gene, suppr...

Here we investigated CD44 protein expression and its polymorphisms in patients with chronic gastritis, precancerous gastric lesions, and gastric cancer; and we evaluated our result with the risk of CD44 protein expression and clinicopathological characteristics. Our results obtained by analyzing 162 gastric cancer patients, 125 chronic gastritis, and 165 precancerous gastric lesions from three ...

Endoscopic procedures are the gold standard in identifying, monitoring and treating gastrointestinal system lesions. The evaluation of benign, precancerous and malignant characteristics of these lesions requires good endoscopic inspection and precise pathological examination. Pyloric gland adenoma is a rare precancerous lesion defined in recent years and herein is reviewed in the present case a...

We examined whether colonization of selected oral pathogens is associated with gastric precancerous lesions in a cross-sectional study. A total of 119 participants were included, of which 37 were cases of chronic atrophic gastritis, intestinal metaplasia, or dysplasia. An oral examination was performed to measure periodontal indices. Plaque and saliva samples were tested with real-time quantita...

It is h igh ly desirable to be able to recognize lesions l ikely to develop into cancer. One reason for so m u c h difference of op in ion is that the p rob lem has not been clarified by exper imenta l work on animals . A major research project in the Barnard Free Skin and Cancer Hosp i ta l is the in tegra t ion of changes that occur in ep ide rma l me thy lcho lan th rene carcinogenesis of mi...