نتایج جستجو برای: prednisone

تعداد نتایج: 9193  

Journal: :Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2015
Karim Fizazi Robert Jones Stephane Oudard Eleni Efstathiou Fred Saad Ronald de Wit Johann De Bono Felipe Melo Cruz George Fountzilas Albertas Ulys Flavio Carcano Neeraj Agarwal David Agus Joaquim Bellmunt Daniel P Petrylak Shih-Yuan Lee Iain J Webb Bindu Tejura Niels Borgstein Robert Dreicer

PURPOSE Orteronel (TAK-700) is an investigational, nonsteroidal, reversible, selective 17,20-lyase inhibitor. This study examined orteronel in patients with metastatic castration-resistant prostate cancer that progressed after docetaxel therapy. PATIENTS AND METHODS In our study, 1,099 men were randomly assigned in a 2:1 schedule to receive orteronel 400 mg plus prednisone 5 mg twice daily or...

Journal: :Haematologica 2005
Tadeusz Robak Jerzy Z Blonski Marek Kasznicki Joanna Góra-Tybor Anna Dmoszyñska Aleksander Skotñicki

We present the long-term follow-up and results of subsequent treatments in patients with chronic lymphocytic leukemia treated initially with cladribine + prednisone or chlorambucil + prednisone in a randomized, cross-over study. We found higher complete and overall responses rates in patients who received cladribine + prednisone as first and second-line treatment but no significant differences ...

Journal: :British medical journal 1973
H G Morgan J Boulnois C Burns-Cox

2016
Francesca Bandinelli Francesco Scazzariello Emanuela Pimenta da Fonseca Mittermayer Barreto Santiago Claudio Marcassa Francesca Nacci Marco Matucci Cerinic

BACKGROUND Oral glucocorticoids (GCs) have been shown to be effective in reducing the inflammatory symptoms of rheumatoid arthritis, but their use is not supported by evidence in spondyloarthritis (SpA). Modified-release (MR) oral prednisone taken at bedtime has been shown to be more effective than immediate-release prednisone taken in the morning. The efficacy of low-dose MR prednisolone in pa...

2017
Dingwei Ye Yiran Huang Fangjian Zhou Keji Xie Vsevolod Matveev Changling Li Boris Alexeev Ye Tian Mingxing Qiu Hanzhong Li Tie Zhou Peter De Porre Margaret Yu Vahid Naini Hongchuan Liang Zhuli Wu Yinghao Sun

Objective This double-blind, placebo-controlled phase 3 study was designed to compare efficacy and safety of abiraterone acetate + prednisone (abiraterone) to prednisone alone in chemotherapy-naïve, asymptomatic or mildly symptomatic metastatic castration-resistant prostate cancer (mCRPC) patients from China, Malaysia, Thailand and Russia. Methods Adult chemotherapy-naïve patients with confir...

Journal: :Gut 1978
R C Smith J Rhodes R V Heatley L E Hughes D L Crosby B I Rees H Jones K T Evans B W Lawrie

The long-term effect of prednisone in Crohn's disease has been examined in a double-blind controlled trial. Clinical relapse, recurrence, and extension of the disease were examined in 64 patients followed-up for up to three years. Fourteen patients were withdrawn because of severe symptoms (eight on prednisone and six controls); the withdrawal rate in both groups was 30% at three years. Nine ot...

Journal: :Neurology 2004
Santiago Restrepo

There is no cure yet for MD. There are some treatments that can improve symptoms and quality of life. One of the targets for recent new therapies has been to improve muscle strength. For several years prednisone has been used for this purpose. Prednisone is a medication that decreases inflammation in the body. Prednisone has serious and common side effects, however, including weight gain, catar...

2013
Nurimar Conceição Fernandes Mariana Menezes

In this study, five cases of pemphigus vulgaris and two cases of pemphigus foliaceus were treated with cyclophosphamide pulse therapy associated with prednisone, resulting in the need for a smaller maintenance dose of prednisone. In three cases of pemphigus vulgaris and one case of pemphigus foliaceus, dexamethasone and cyclophosphamide pulse therapy associated with prednisone helped the lesion...

Journal: :Cancer 1982
D Hollister M Coleman

Prolymphocytic leukemia is characterized by marked splenomegaly, distinctive cellular morphologic characteristics, and a poor clinical course. Five patients with typical PL were treated systematically with vincristine/prednisone, chlorambucil/prednisone, splenic irradiation, splenectomy, and other chemotherapy regimens. No patient responded to vincristine/prednisone. Two patients responded to c...

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