OBJECTIVE To compare inflammatory mediators in the cord blood of premature newborn infants with premature rupture of membranes (PROM) and intact membranes. METHODS Eighty-nine premature neonates with gestational age of 27-34 weeks that delivered in Ghaem Hospital in Mashhad, Iran from June 2005 to March 2006 were enrolled in a prospective observational study, and their umbilical cord plasma w...

Neonatal compartment syndrome is rare, and the diagnosis is often missed or delayed because other ischemic diseases can mimic clinical signs observed on the skin. A premature newborn infant presented with skin lesions during the first hours of life that were recognized as the sentinel finding in compartment syndrome of the newborn. We restored normal function by emergency surgery. The authors h...

background: prematurity is the main cause of death in infants under one years of age and is the main reason for nicu hospitalization. the stressful environment of nicu exposes preterm infants to inappropriate stimuli. this study aimed to determine and compare the mean of heart rate and oxygen saturation of premature infants before and during a designed program in nicu. methods: in a clinical tr...

Received May 19, 2001 Abstract We report a premature newborn who developed circulatory collapse 46 hours after birth due to cardiac tamponade. Echocardiography revealed large circumferential pericardial effusion. Pericardiocentesis yielded 12 ml of clear straw-colored fluid with high glucose level of 102.9 mmol/L. The neonate improved after the procedure. Pericardial tamponade is a rare complic...

In this case report, it is our purpose to relate our findings concerning bloody discharge as an ominous sign in the conservative management of premature rupture of membranes, (PROM) as well as to present relevant findings of the amniotic band syndrome such as amputation of one leg, constriction rings in two fingers, and pseudosyndactyly in the toes of the remaining foot in a 28 week old ne...

Subcutaneous fat necrosis of the newborn is an uncommon disorder occurring during the prenatal stage. Generally occurring in full-term neonates or during the first four weeks after a traumatic delivery, the disorder is characterized by the appearance of hard subcutaneous nodules or plaques on the trunk, buttocks or thighs. It is normally a benign and transient condition, although it may be comp...

A rare clinical case of intraplacental intervillous hemorrhage (Kline's hemorrhage) is presented. After delivery of a premature newborn (810 g/35 cm) in 27th week of uncomplicated pregnancy, peripartum observation of the premature placenta (270 g, 16 x 16 x 1.8) suggested multiple intraplacental cavernae with semifluid blood and fresh coagula and fresh marginal (partial) placental abruption. Th...

We examined 30 newborn infants for respiratory compromise before, during, and after placement in a recommended car seat restraining device. Twelve infants were premature with a history of apnea, eight were premature without known apnea, and 10 were born at term. Both premature groups had significant decreases in oxygen saturation while in the car seat (P less than 0.01) and more frequent desatu...

Whole-genome and whole-exome sequencing for clinical applications is now an integral part of medical genetics practice. The term newborn screening refers to public health programs designed to screen newborns for various treatable metabolic conditions, by measuring levels of circulating blood metabolites. The availability and significant decrease in sequencing costs has raised the question of wh...

Newborns, and especially premature newborns, are at significant risk for developing hypotension in the first week or two after birth. The etiology of hypotension in the newborn may vary, but the very low birth weight and extremely low birth weight preterm infants are less likely to respond to conventional cardiovascular support when they develop hypotension. This article reviews the least conve...