The formation of protein aggregates is a hallmark neurodegenerative diseases. Observations on patient samples and model systems demonstrated links between aggregate declining mitochondrial functionality, but causalities remain unclear. We used Saccharomyces cerevisiae to analyze how processes regulate the behavior aggregation-prone polyQ derived from human huntingtin. Expression Q97-GFP rapidly...

Structural changes in the European natural gas market such as liberalization, increasing domestic demand, and increasing import dependency have triggered new attempts to model these markets accurately. In this paper, we propose an exhaustive model of the European natural gas supply including the possibility of strategic behaviour of the agents along the value-added chain. We structure it as a t...

Previous work has shown that when yeast mitochondria are incubated in the presence of the presequence peptide pL4(1-22), the peptide is imported and accumulates within the mitochondrial membranes, presumably at the import sites. If the extramitochondrial concentration of peptide is sufficiently high, enough peptide accumulates within the import sites to prevent the uptake of authentic precursor...

Pollutants of Carbon flow virtually by streaming the Goods and services among the countries. Due to the Carbon Footprint (CFP) in economical divisions as well as subdivisions in Iran, the main objective of this paper is to specify the effects of Carbon footprint on import and export of various sections in the framework of Computable General Equilibrium Model. It’s used the social accounting mat...

There are many compressor stations along long-distance natural gas pipelines. Natural gas can be transported using different boot programs and import pressures, combined with temperature control parameters. Moreover, different transport methods have correspondingly different energy consumptions. At present, the operating parameters of many pipelines are determined empirically by dispatchers, re...

In this article, real exchange rate behavior and its effects on macroeconomic variables are studied by explaining two models; impulse function and forecasting predicted error decomposition. Studies show that high artificial currency value has caused domestic and foreign accounts equilibrium disturbance and foreign income decrease due to the slackening of commercial and agricultural activities, ...

in this paper the trade restrictiveness of agricultural policies in iran was measured by the triindex for the nine major agricultural products including wheat, rice, barely, maize, soybean,meat (beef meat), soybean oil, sugar and banana over the period 1981 to 2007. the main resultsindicate that there is no trend in above index and high volatility especially in 2006 and 2007years due to conside...

The Radiological Research Accelerator Facility at Columbia University has recently added a UV microspot irradiator to a microbeam irradiation platform. This UV microspot irradiator applies multiphoton excitation at the focal point of an incident laser as the source for cell damage, and with this approach, a single cell within a 3D sample can be targeted and exposed to damaging UV. The UV micros...

The oil and gas industry is involved in a global supply-chain that includes domestic and international transportation, ordering and inventory visibility and control, materials handling, import/export facilitation and information technology. Thus, the industry offers a classic model for implementing supply-chain management techniques. In a supply-chain, a company is linked to its upstream suppli...