OBJECTIVES Surgical management of patients following zoledronic acid therapy is particularly difficult, since the dental extraction is the main cause of BRONJ. METHODS A case-control study was conducted on 176 patients treated with intravenous (IV) bisphosphonates for oncologic pathologies who also underwent dental extractions. The study was divided randomly into two groups: 91 were treated w...

The purpose of this study was to perform a number of preliminary in vitro evaluations on an array of modified gelatin gel sponge scaffolds for use in a bone graft application. The gelatin gels were modified through the addition of a number of components which each possess unique properties conducive to the creation and regeneration of bone: a preparation rich in growth factors (PRGF, a bioactiv...

Purpose: The aim of this study was to evaluate the split-crest technique with ultrasonic bone surgery for implant placement in patients with narrow ridges, focusing on the status of soft and hard tissues and on implant success rate, at least 6 months after implant loading. Materials and Methods: During September 2007 and November 2008, 15 patients received 37 implants (BTI implants) with split-...

In the wake of the ‘east Asian crisis’, many commentators have argued that the IMF should ‘return to basics’ and that the Poverty Reduction and Growth Facility through which the Fund makes long term loans to poor countries should be abandoned. To various degrees, they are critical of the Fund’s involvement with developing countries and suggest that the World Bank and aid donors should replace i...

Osteoarticular pathologies very often require an implementation therapy to favor regeneration processes of bone, cartilage and/or tendons. Clinical approaches performed on osteoarticular complications in dogs constitute an ideal model for human clinical translational applications. The adipose-derived mesenchymal stem cells (ASCs) have already been used to accelerate and facilitate the regenerat...

background and aims. plasma rich in growth factors (prgf) is a concentrated suspension of growth factors, which is used to promote periodontal tissue regeneration. the aim of this randomized, controlled, clinical trial was to evaluate of the treatment of grade ii mandibular molar furcation involvement using autogenous bone graft with and without prgf. materials and methods. in this double-blind...

background and aims. a combination of guided tissue regeneration (gtr), bovine porous bone mineral (bpbm), and platelet rich plasma has been already applied for the regeneration of intrabony defects. the aim of this study was to determine the role of plasma rich in growth factor (prgf) alone in the periodontal regeneration of intrabony defects in humans as compared with bpbm/gtr technique. mate...