PURPOSE To report the results of screening first degree relatives of persons identified with primary open angle glaucoma in a tertiary eye hospital glaucoma services. DESIGN A cross-sectional study of first degree relatives of persons with primary open angle glaucoma. MATERIALS AND METHODS First degree relatives of patients identified with primary open angle glaucoma were invited to partici...

Although glaucoma is a major global cause of blindness, the lack of a uniform definition of the disease in its different forms makes it difficult to assess its public health impact. By considering the common features of glaucoma, we have analysed available data on the three main forms of the disease: congenital/hereditary glaucoma, primary open-angle, and primary angle-closure glaucoma. A simpl...

PURPOSE To prospectively study the success rates and complications of viscocanalostomy. METHODS Prospective nonrandomized case series of 46 eyes (46 patients) with medically uncontrolled primary and secondary open angle glaucoma. All patients in the study underwent viscocanalostomy. Control of intraocular pressure was used to measure success. Pre and postoperative glaucoma medications, visual...

PURPOSE The purpose of this to investigate whether selective laser trabeculoplasty (SLT) has any effect on the success of trabeculectomy. PATIENTS AND METHODS Thirteen-one eyes of 29 primary open-angle glaucoma patients who underwent SLT before trabeculectomy and 29 eyes of 27 patients with the same inclusion criteria which underwent trabeculectomy without prior SLT in the Sifa University and...

Purpose Glaucoma significantly affects the quality of life (QoL) of a patient. Despite the huge number of glaucoma patients in India, not many, QoL studies have been carried out. The purpose of the present study was to evaluate the QoL in Indian patients with varying severity of glaucoma. Methods This was a hospital-based, cross-sectional, analytical study of 180 patients. The QoL was assesse...

A single-nucleotide polymorphism (SNP) rs4236601 at the CAV1/CAV2 locus is associated with primary open-angle glaucoma (POAG). Rs4236601 is common in Caucasians but rare in East Asians. Here we conducted a haplotype-tagging SNP analysis followed by replication in a total of 848 POAG cases and 1574 controls drawn from 3 cities in China and 1 city in Japan. Two SNPs, rs4236601 (odds ratio [OR] = ...

ous fluid by producing 0.5-mm holes. There is no reference given to this observation, therefore it is not clear how this observation was determined. The article states that the laser fiber is 200  m. It is unclear how this would create 500m ostia. On page 286, an aiming beam is mentioned in the Surgical Technique section. However, unless the AIDA laser system has been modified, and this is not...

We present the results of a double-blind trial comparing the efficacy of a single dose combination of guanethidine 3 % and adrenaline 0 5 % with that of adrenaline 1 % alone in reducing the intraocular pressure of eyes suffering from chronic open-angle glaucoma. The mean fall in ocular tension with the combined therapy was 10-67 mmHg, and with adrenaline 1% 6-31 mmHg, 24 hours after the commenc...

PURPOSE To evaluate the association between clinical parameters and the diagnosis of progression using VFI (Visual Field Index) and AGIS (Advanced Glaucoma Intervention Study) score in primary open angle glaucoma. METHODS Retrospective study of 517 visual fields of 78 eyes with primary open angle glaucoma analyzed with VFI and AGIS score. Clinical data registered included: age, sphere, pachim...