We have previously shown that ~10% of all eukaryotic mRNAs contain potential programmed -1 ribosomal frameshifting (-1 PRF) signals and that some function as mRNA destabilizing elements through the Nonsense-Mediated mRNA Decay (NMD) pathway by directing translating ribosomes to premature termination codons. Here, the connection between -1 PRF, NMD and telomere end maintenance are explored. Func...

BACKGROUND Autologous platelet concentrate has been used to improve the function and regeneration of injured tissues. Tendinopathies are common in clinical practice, although long-term treatment is required. On the basis of lead time, we compared the effect of using platelet-rich plasma (PRP) and platelet-rich fibrin (PRF) in repairing rat Achilles tendon. METHODS The effectiveness of usi...

A method based on conceptual tools of predictive control is described for tackling tracking problems of uncertain linear systems wherein pointwise-in-time input and/or state inequality constraints are present. The method consists of adding to a primal compensated system a nonlinear device called Predictive Reference Filter (PRF) which manipulates the desired reference in order to fullll the pre...

BACKGROUND Pulsed radiofrequency (PRF) application to the dorsal root ganglia can reduce neuropathic pain (NP) in animal models, but the effect of PRF on damaged peripheral nerves has not been examined. We investigated the effect of PRF to the rat sciatic nerve (SN) on pain-related behavior and SN ultrastructure following chronic constriction injury (CCI). METHODS The analgesic effect was mea...

The high squint diving SAR is widely used to provide the information in advance. Large squint angle deduces the deeper coupling of range and azimuth of SAR echoes which makes SAR imaging more difficult. Especially, the large range migration of the deep couple heavily burdens the imaging processing time and storage units. The diving motion of platform worsens the situation. This paper proposes t...

Platelet-released growth factors (PRGF) and its related clinically used formulations (e.g., Vivostat Platelet-Rich Fibrin (PRF®)) contain a variety of chemokines, cytokines, and growth factors and are therefore used to support healing of chronic, hard-to-heal, or infected wounds. Human beta-defensin-3 (hBD-3) is an antimicrobial peptide inducibly expressed in human keratinocytes especially upon...

In tomato, resistance to Pseudomonas syringae pv. tomato (Pst) strains expressing the avirulence gene avrPto requires the presence of at least two host genes, designated Pto and Prf. Here we report that Prf encodes a protein with leucine-zipper, nucleotide-binding, and leucine-rich repeat motifs, as are found in a number of resistance gene products from other plants. prf mutant alleles (4) were...

Traditionally, modes of Message Authentication Codes(MAC) such as Cipher Block Chaining (CBC) are instantiated using block ciphers or keyed Pseudo Random Permutations(PRP). However, one can also use domain preserving keyed Pseudo Random Functions(PRF) to instantiate MAC modes. The very first security proof of CBC-MAC [BKR00], essentially modeled the PRP as a PRF. Until now very little work has ...

OBJECTIVE The primary objective of this study was to compare clinically and radiographically the efficacy of autologous platelet rich fibrin (PRF) and autogenous bone graft (ABG) obtained using bone scrapper in the treatment of intrabony periodontal defects. MATERIALS AND METHODS Thirty-eight intrabony defects (IBDs) were treated with either open flap debridement (OFD) with PRF or OFD with AB...