Mineral trioxide aggregate (MTA) has been recommended for pulp capping, pulpotomy, apical barrier formation in teeth with open apexes, repair of root perforation and root canal obturation. Since, its introduction in 1993 by Torabinejad numerous studies have been published regarding various aspects of this material. The aim of this review was to consider MTA as root canal sealer and various labo...

AIM To examine the clinical and radiographic appearance of teeth with immature apices that were treated by single step procedure using mineral trioxide aggregate (MTA). SUMMARY Creation of a physiological hard tissue barrier with calcium hydroxide in a nonvital tooth although quite predictable has certain limitations, such as the very long duration of the treatment spread over multiple visits...

Background: Mineral trioxide aggregate (MTA) exhibits several properties of an ideal root-end filling. It, however, has certain disadvantages such as long setting time, difficult handling characteristics, and limited antimicrobial activity. In order to improve its properties, several commonly used reagents have been used instead of sterile water. Hence the objective of this study was to evaluat...

INTRODUCTION Mineral trioxide aggregate (MTA) was developed because existing materials did not have the ideal characteristics for orthograde or retrograde root-end fillings. MTA has been recommended primarily as a root-end filling material, but it has also been used in pulp capping, pulpotomy, apical barrier formation in teeth with open apexes, repair of root perforations, and root canal fillin...

OBJECTIVE The aim of this study was to evaluate the marginal adaptation of Biodentine in comparison with Mineral Trioxide Aggregate (MTA) and Intermediate Restorative Material (IRM), as a root end filling material, using Scanning Electron Microscopy (SEM). MATERIALS AND METHODS Thirty permanent maxillary central incisors were chemo-mechanically prepared and obturated. Three millimetres of the...

5'-methylthioadenosine (MTA) is a nucleoside generated from S-adenosylmethionine (AdoMet) during polyamine synthesis. Recent evidence indicates that AdoMet modulates in vivo the production of inflammatory mediators. We have evaluated the anti-inflammatory properties of MTA in bacterial lipopolysaccharide (LPS) challenged mice, murine macrophage RAW 264.7 cells, and isolated rat hepatocytes trea...

introduction: pulpotomy of carious primary teeth with an exposed pulp is a common treatment option. pulpotomy has been conducted with various medicaments over the years. the aim of this study was to evaluate clinical and radiographic success of primary vital pulpotomy with proroot and root mta. materials and methods: in this randomized clinical trial, children aged between 3-7 years who met the...

BACKGROUND Inflammation and fibrogenesis are directly related to chronic liver disease progression, including hepatocellular carcinoma (HCC) development. Currently there are few therapeutic options available to inhibit liver fibrosis. We have evaluated the hepatoprotective and anti-fibrotic potential of orally-administered 5'-methylthioadenosine (MTA) in Mdr2(-/-) mice, a clinically relevant mo...