In the pharmaceutical industry, a number of tests such as content uniformity and dissolution testing are usually performed at various stages of drug manufacturing process to ensure that the drug product meets standards for identity, strength, quality, purity, and stability of the drug product as specified in the United States Pharmacopedia and National Formulary (USP/NF). The USP/NF provides re...

In this study, 18 copies of PLAVIX tablets containing clopidogrel hydrogensulfate were compared to the innovator drug product for uniformity of mass, impurity profile, content, dissolution properties and stability. In order to be able to separate the R-enantiomer of clopidogrel, an enantiospecific liquid chromatographic method was used to determine the impurities and to perform the assay. The p...

Columbia University and USC, as well as many other universities, have software engineering courses where students work in small teams to develop a product of moderate complexity. Typically such efforts are “closed source” where teams do not (or are forbidden) from sharing information and providing assistance to other teams. There are certainly many justifiable reasons for this such as grading u...

Radiation processing of foods and allied products is one of the important techniques to extend shelf-life. The success of this technology depends on the adequate dose delivery to the food products. The absorbed doses are functions of several irradiation parameters based on the design of the facility. The variable bulk density of the process load is of paramount importance in determining the dos...

Cobalt nanowires with high aspect ratio have been synthesized via a solvothermal chemical process. Based on the shape anisotropy and orientation of the nanowire assemblies, a record high room-temperature coercivity of 10.6 kOe has been measured in Co nanowires with a diameter of about 15 nm and a mean length of 200 nm. As a result, energy product of the wires reaches 44 MGOe. It is discovered t...

Skeletal muscle stem cells from food-producing animals are of interest to agricultural life scientists seeking to develop a better understanding of the molecular regulation of lean tissue (skeletal muscle protein hypertrophy) and intramuscular fat (marbling) development. Enhanced understanding of muscle stem cell biology and function is essential for developing technologies and strategies to au...

Crystallization is a key unit operation that finds extensive applications in pharmaceutical, food and fine chemicals industries . The operating conditions of the crystallization process have a direct effect on the purity, size distribution, shape and polymorphic form of the crystals. These properties in turn affect the efficiencies of the downstream operations such as filtration, drying and for...

Red yeast rice is a Chinese fermented rice product (Monascus purpureus) that some have claimed improves blood circulation by decreasing cholesterol and triglyceride levels in humans. The supplement contains naturally occurring monacolin K, the active ingredient found in Merck's prescription agent lovastatin (Mevacor). Lovastatin is associated with various adverse effects such as myopathy and ab...

A cascaded feedback control strategy for an industrial vapour-phase axial deposition (VAD) process is investigated in this paper. VAD is a widely used process in the creation of high-purity glass for optical fibre. In previous work a soot tip surface temperature controller was developed for the VAD process to reduce the effects of core soot temperature variation on deposition geometry, leading ...

Here, we give a complete description of the entire c-Boomerang Connectivity Table for Gold function over finite fields even characteristic, by using double Weil sums. As by-product, generalize result Boura and Canteaut (IACR Trans. Symmetric Cryptol. 2018(3) : 290–310, 2018) classical boomerang uniformity (see also extended abstract Eddahmani Mesnager at Boolean Functions their Applications (BF...