The cardiac differentiation of embryonic stem (ES) cells was found to involve prodynorphin gene and dynorphin B expression and was associated with the interaction of secreted dynorphin B with cell surface opioid receptors coupled with protein kinase C (PKC) signaling and complex subcellular redistribution patterning of selected PKC isozymes. Here, confocal microscopy revealed the presence of im...

Title of dissertation: STRUCTURAL CHARACTERIZATION OF METAL AND DNA BINDING TO DREAM PROTEIN, A CALCIUM SENSING TRANSCRIPTIONAL REPRESSOR IN PAIN MODULATION Aswani Kumar Valiveti, Doctor of Philosophy, 2006 Dissertation directed by: Dr. James. B. Ames Center for Advanced Research in Biotechnology DREAM (Downstream Regulatory Element Antagonistic Modulator) is the first reported calcium binding ...