نتایج جستجو برای: progestin
تعداد نتایج: 2449 فیلتر نتایج به سال:
CONTEXT Effective contraception is essential in women with prior gestational diabetes mellitus (GDM) but should not increase their already substantial risk of developing type 2 diabetes. OBJECTIVE To determine whether exposure to low-dose oral contraceptives increases the risk of developing type 2 diabetes mellitus in women with recent GDM. DESIGN Retrospective cohort study of 904 Latinas w...
CONTEXT Postmenopausal women have a greater risk than men of developing Alzheimer disease, but studies of the effects of estrogen therapy on Alzheimer disease have been inconsistent. On July 8, 2002, the study drugs, estrogen plus progestin, in the Women's Health Initiative (WHI) trial were discontinued because of certain increased health risks in women receiving combined hormone therapy. OBJ...
Abstract Introduction Oral contraceptive pills (OCPs), which are used by over a quarter of reproductive-age women in the United States (Daniels et al., 2015; Jones 2013), contain either both ethinylestradiol and synthetic progestin, or solely progestin. Through progestin-induced hepatic increases sex hormone binding globulin (SHBG), OCPs have been found to reduce number bioavailable androgens w...
Intrauterine progestins have many important current and potential gynecologic applications. This article describes the evidence for use of intrauterine progestin for common gynecologic conditions beyond its important role in contraception. The pharmacology of and selection criteria for use of the levonorgestrel intrauterine device is discussed, and the evidence for use of intrauterine progestin...
Currently, there are mounting data suggesting that HIV-1 acquisition in women can be affected by the use of certain hormonal contraceptives. However, in non-human primate models, endogenous or exogenous progestin-dominant states are shown to increase acquisition. To gain mechanistic insights into this increased acquisition, we studied how mucosal barrier function and CD4+ T-cell and CD68+ macro...
CONTEXT In the Women's Health Initiative randomized, placebo-controlled trial of estrogen plus progestin, after a mean intervention time of 5.6 (SD, 1.3) years (range, 3.7-8.6 years) and a mean follow-up of 7.9 (SD, 1.4) years, breast cancer incidence was increased among women who received combined hormone therapy. Breast cancer mortality among participants in the trial has not been previously ...
Introduction: This article discusses reproductive health for a young woman with positive HIV during postnatal care. Discussion: In HIV-positive patients, ART treatment protocols may vary. Hormonal contraception in combined oral (COC), progestin-only pill, depo-medroxyprogesterone acetate (DMPA), and implant are considered safe. An intrauterine device (IUD) is also safe women. Cervical cancer sc...
Progestin is a synthetic form of progesterone [4], a naturally occurring hormone [5], which plays an important role in the female reproductive cycle. During the 1950s two types of progestin [6] that were later used in birth control [7] pills were created, norethindrone [8] and norethynodrel [9]. In 1951 Carl Djerassi [10] developed norethindrone [8] at Syntex [11], SA Laboratories located in Me...
Progestins are synthetic compounds that mimic the effects of progesteron. For over 50 years, oral progestins have been demonstrated to be effective in the treatment of endometriosis. They were reported to reduce or eliminate pain symptoms in approximately 90% of the patients. Progestins are available in many forms, including oral preparations, injections, subdermal implants and intrauterine sys...
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