OBJECTIVES This study sought to investigate whether prolongation of the heart rate-corrected QT (QTc) interval is a risk factor for sudden cardiac death in the general population. BACKGROUND In developed countries, sudden cardiac death is a major cause of cardiovascular mortality. Prolongation of the QTc interval has been associated with ventricular arrhythmias, but in most population-based s...

BACKGROUND Increased aerobic capacity can reduce the incidence of cardiovascular disease and the mortality rate. On the other hand, a prolonged heart rate corrected-QT (QTc) interval is associated with an increased risk of arrhythmias, cardiac sudden death and coronary artery disease. AIMS The association of the aerobic capacity and coronary risk factors with QTc interval was investigated in ...

We read with great interest the article by Bestas et al1 entitled “The effect of adrenaline on desflurane-induced prolonged QTc interval: a randomized double-blind trial”, which is published in the current issue of European Review for Medical and Pharmacological Sciences. The Authors1 investigated the effect of adrenaline on desflurane-induced prolonged corrected QT (QTc) interval. They mention...

Few data are available on the association between the prolonged heart rate-adjusted QT (QTc) interval and high blood pressure in elderly individuals, particularly in subjects over 80 years old. The aim of the present study was to determine the association between the QTc interval and blood pressure in 80-year-old subjects. This study was part of the 8020 Data Bank Survey, which was designed to ...

Cardiac arrest due to torsades de pointes (TdP) is an uncommon but potentially catastrophic event associated with QT interval-prolonging drugs [1]. Numerous medications that may cause TdP are available for use in clinical practice, and include drugs for management of cardiovascular diseases, primarily arrhythmias, but also noncardiovascular agents from multiple classes, including antiinfectives...

OBJECTIVE Our aim was to assess whether severe hypoglycemic attacks were cross-sectionally associated with abnormalities of the QTc interval in type 1 diabetic patients. RESEARCH DESIGN AND METHODS The study included 3,248 type 1 diabetic patients from the EURODIAB IDDM Complications Study. Severe hypoglycemia was defined as an attack serious enough to require the help of another person. A co...

BACKGROUND Methadone is a synthetic opioid, used in treatment of chronic pains. The current study was carried out to evaluate the QTc interval in Iranian causalities (Janbazan) of Iran-Iraq war receiving maintenance methadone treatment. MATERIALS AND METHODS In 2010, one hundred war causalities in Isfahan who chronically take daily dose of 20 mg or more of methadone (more than 2 weeks), and d...

ramadan fasting is one of the most important religious duties of muslims, that its effect on the heart has not been determined yet. our objective was to evaluate the effect of ramadan fasting on ventricular repolarization as assessed by qt interval, corrected qt interval, qt dispersion or corrected qt dispersion. sixthy healthy subjects aged 20 to 35 years were dispersion included in this study...

Introduction: Patients with type 2 diabetes mellitus (DM) are at increased risk of dying from cardiovascular diseases. Elevated cardiovascular risk in this population persists even after other conventional cardiovascular risk factors are eliminated or reduced, suggesting that there are other, incompletely understood, mechanisms which are increasing cardiovascular risk in such patients. Ventricu...