نتایج جستجو برای: propargylamine derivatives

تعداد نتایج: 104954  

2003
Luc Florack Remco Duits

Gaussian scale space permits one to compute image derivatives. The limitation to some finite order is not inherent in the paradigm itself (Gaussian blurred functions are always smooth), but is caused by the interplay of (at least) two external factors. One is the ratio of the Gaussian scale parameter versus the atomic scale that limits physically or perceptually meaningful sizes (e.g. pixel siz...

Journal: :Journal of dairy science 2008
B N Janicek P J Kononoff A M Gehman P H Doane

Two studies were performed to evaluate the effects of dried distillers grains with solubles (DDGS) on the lactational performance of dairy cows. The intent of experiment 1 was to evaluate the effects of feeding increasing concentrations of DDGS on the feed intake and production of Holstein dairy cows. Twenty multiparous Holstein cows averaging 76 +/- 24 d in milk and 638 +/- 68 kg of body weigh...

2014
Moritz Schubert Dieter Schollmeyer Siegfried R. Waldvogel

The title compound, C17H27O8P, was prepared by Michaelis-Arbuzov reaction of ethyl 2-bromo-2-(2,3,4-tri-meth-oxy-phen-yl)acetate and triethyl phosphite. Such compounds rarely crystallize, but single crystals were recovered after the initial oil was left for approximately 10 years. The bond angle of the sp (3)-hybridized C atom connecting the benzene derivative with the phospho unit is widened m...

Journal: :The Journal of organic chemistry 2001
J Li H Jiang M Chen

Many metals or their complexes can catalyze the cyclotrimerization of alkynes to give benzene derivatives.1-9 Among these catalysts, palladium chloride10 and its bis(benzonitrile) complex11 are the most convenient. In these reactions, the yields of benzene derivatives generally depend on the substituents of alkynes. In the past 50 years, the regioand chemoselectivity for the cyclotrimerization ...

2006
Junichi Kitanaka Nobue Kitanaka Motohiko Takemura

Methamphetamine (METH) abuse is a serious health and social problem worldwide. At present, however, there are no effective medications for the treatment of METH abuse. Of the intracellular METH target proteins, monoamine oxidase (MAO) is involved in the regulation of monoaminergic tone in the brain, resulting in the modulation of METH-induced behavioral abnormalities in mammals. The METH-induce...

Journal: :Catalysts 2023

Density functional theory (DFT) was used to investigate the three-component coupling reactions of aldehydes, alkynes, and amines (A3 coupling) using N-heterocyclic carbene silver as catalyst. This study reveals that addition reaction between catalyst phenylacetylene (PAE) forms Ag_PAE. Subsequently, one hydrogen atom Ag_PAE migrates nitrogen Amine. Thereafter, amine aldehyde condensation genera...

Journal: :Drug metabolism and disposition: the biological fate of chemicals 2000
D A Durden L E Dyck B A Davis Y D Liu A A Boulton

(R)-N-(2-Heptyl)-N-methylpropargylamine (R-2HMP) is a monoamine oxidase inhibitor and putative antiapoptotic agent analogous to (R)-deprenyl. In the rat, the major amine metabolites of R-2HMP have been identified as (R)-N-2-heptylmethylamine (R-2HMA), (R)-N-2-heptylpropargylamine (R-2HPA), and (R)-2-heptylamine (R-2HA). After R-2HMP was administered s.c. to male Wistar rats, it was observed tha...

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