OBJECTIVE To compare the cost effectiveness of prophylaxis with a low-molecular-weight heparin with that of prophylaxis with unfractionated heparin for the prevention of venous thromboembolism in acutely ill medical inpatients. STUDY DESIGN Cost-effectiveness analysis based on decision-tree model. PARTICIPANTS AND METHODS A hypothetical cohort of 10 000 patients was assumed to receive eithe...

OBJECTIVE To evaluate incidence and risk factors of postoperative meningitis, with special emphasis on antibiotic prophylaxis, in a series of 6243 consecutive craniotomies. METHODS Meningitis was individualized from a prospective surveillance database of surgical site infections after craniotomy. Ventriculitis related to external ventricular drainage or cerebrospinal fluid shunt were excluded...

INTRODUCTION Venous thromboembolism (VTE) is associated with considerable morbidity and mortality in stroke patients. The purpose of our survey was to establish the current methods of VTE prophylaxis practiced by Polish neurologists. We also aimed to determine whether there is enough variation in practice to justify the development of an evidence-based guideline for VTE prevention. MATERIAL A...

BACKGROUND Trauma surgeons use a variety of methods to prevent venous thromboembolism (VT). The rationale for their use frequently is based on conclusions from research on nontrauma populations. Existing recommendations are based on expert opinion and consensus statements rather than systematic analysis of the existing literature and synthesis of available data. The objective is to produce an e...

intravenous chemotherapy is an important mean for the treatment of cancers. infusion phlebitis (ph) is a common and acute complication of chemotherapy. the frequency of ph is about 70% in patients undergoing chemotherapeutic management. it can induce the pain, increase the risk of thrombophlebitis, lead to incomplete follow-up, and thereby, affect the patient’s health status. respecting the gre...

BACKGROUND Prophylaxis with factor (F)VIII is considered the optimal treatment for managing hemophilia A patients without inhibitors. OBJECTIVES To compare the efficacy of two prophylaxis regimens (primary outcome) and of on-demand and prophylaxis treatments (secondary outcome), and to continue the evaluation of immunogenicity and overall safety of the ADVATE Antihemophilic Factor (Recombinan...

ABSTRACT BACKGROUND: Endoscopic retrograde cholangiopancreatography is a widely used therapeutic modality for the pancreaticobiliary tree. However, it responsible highest rates of complications among endoscopic procedures, especially post-endoscopic pancreatitis. The preventive methods include mechanical and pharmacological approaches, such as use non-steroidal anti-inflammatory drugs. OBJECTIV...

Abstract Background The incidence and characteristics of deep vein thrombosis (DVT) following total knee arthroplasty (TKA) without pharmacologic prophylaxis have not been fully investigated. This study aimed to determine whether there are any differences in the incidence, location, DVT TKA with prophylaxis. Methods A 156 knees were retrospectively evaluated for by duplex ultrasound on postoper...

BACKGROUND Data regarding both rates of acute respiratory illness in health care workers and experience with long-term antiviral prophylaxis are sparse. OBJECTIVE To determine the efficacy and tolerability of oseltamivir prophylaxis versus seasonal influenza vaccine for the prevention of influenza among health care workers. METHODS We conducted a pilot, randomized control study during the 2...

INTRODUCTION Effective strategies for prevention of venous thromboembolism (VTE) are widely available, but still remain underused, mainly in our country. OBJECTIVE Our aim was to verify whether the implementation of a guideline for VTE prophylaxis for surgical patients influenced the prescription of prophylaxis by the medical staff. METHODS This was a retrospective preintervention-postinter...