In this chapter, we have reviewed side effects reported for corticotrphins, systemic glucocorticoids, and prostaglandin analogues from January 2020 to June 2021. We used PUBMED, EMBASE International Pharmaceutical Abstracts (IPA) as our search engines. Adrenocorticotropic hormone (ACTH) has found multiple uses but are associated with adverse on cardiac function nervous system. The corticosteroi...