Prostate imaging analysis is difficult in diagnosis, therapy, and staging of prostate cancer. In clinical practice, Magnetic Resonance Imaging (MRI) is increasingly used thanks to its morphologic and functional capabilities. However, manual detection and delineation of prostate gland on multispectral MRI data is currently a time-expensive and operator-dependent procedure. Efficient computer-ass...

The human kallikrein 5 protein (hK5) is expressed in many normal tissues, most notably in skin, breast, salivary gland and esophagus. It has also been shown to be a potential biomarker for breast, ovarian and testicular cancer. Human kallikrein 3 (hK3; prostate-specific antigen) is the most useful marker for adenocarcinoma of the prostate gland. The aim of this study was to determine whether hK...

Prostate cancer (PCa) is diagnosed by means of needle biopsies typically guided by transrectalultrasound (TRUS). TRUS provides an inexpensive and effective means of visualizing gland anatomy and systematically directing each biopsy needle to a specific region within the gland. However, identification of cancerous regions in the prostate cannot be performed reliably using TRUS imaging or any oth...

Abstract Purpose of Review The main purpose this paper review is to highlight the latest ultrasound (US) imaging technologies prostate gland, an organ increasingly at center attention in field oncological diseases male sex, which needs a 360° evaluation order obtain tailored therapeutic planning. Specialist urological designated for purpose, together with integrated currently tends focus more a...

BACKGROUND Prostate-specific antigen densities have limited success in diagnosing prostate cancer. We emphasise the importance of the peripheral zone when considered with its cellular constituents, the "prostatocrit". OBJECTIVE Using zonal volumes and asymmetry of glandular acini, we generate a peripheral zone acinar volume and density. With the ratio to the whole gland, we can better predict...

Background: Rat prostate gland which is used in various investigation has considerable morphological differences with other mammals. There are few reports about its structure. So, this study was carried on for determining of histomorphological structure of rat prostate. Materials and Methods: Five healthy adult male rats with average weight 20 ± 180 g and approximately 3 - 3.5 months age were s...

Whereas in all other vertebrates the Müllerian ducts of genetic males are aborted during development, under the influence of Müllerian-inhibiting substance, in the caecilian amphibians they are retained as a pair of functional glands. It has long been speculated that the Müllerian gland might be the male accessory reproductive gland but there has been no direct evidence to this effect. The pres...

This article is addressing the role of androgen deprivation therapy (ADT) in prostate brachytherapy. No randomized trials to date evaluating the efficacy of hormonal therapy combined with brachytherapy. Many retrospective trials assessed the role of neoadjuvant androgen deprivation and interstitial permanent prostate brachytherapy in an effort to shrink the prostate gland and to facilitate the ...

The molecular basis of active ion transport in secretory glands such as the prostate is not well characterized. Rat nongastric H-K-ATPase is expressed at high levels in distal colon surface cell apical membranes and thus is referred to as "colonic." Here we show that the ATPase is expressed in rodent prostate complex in a lobe-specific manner. RT-PCR and Western blot analyses indicate that rat ...

Recent technological developments in External Body Radiation Therapy (EBRT), such as intensity-modulated radiation therapy and Image-Guided Radiation Therapy (IGRT), have confirmed the advantages of delivering high doses to achieve optimal tumor-control outcomes and a significant reduction of digestive and urinary toxicities in localized prostate cancer patients. The use of fiducial markers is ...