نتایج جستجو برای: protocatechuic acid

تعداد نتایج: 747494  

2010
Premkumar Jayaraman Meena K Sakharkar Chu Sing Lim Thean Hock Tang Kishore R. Sakharkar

In this study the in vitro activities of seven antibiotics (ciprofloxacin, ceftazidime, tetracycline, trimethoprim, sulfamethoxazole, polymyxin B and piperacillin) and six phytochemicals (protocatechuic acid, gallic acid, ellagic acid, rutin, berberine and myricetin) against five P. aeruginosa isolates, alone and in combination are evaluated. All the phytochemicals under investigation demonstra...

Journal: :Drug metabolism and disposition: the biological fate of chemicals 2008
Furong Qiu Rong Zhang Jianguo Sun A Jiye Haiping Hao Ying Peng Hua Ai Guangji Wang

The potential for herb-drug interactions has recently received greater attention worldwide, considering the fact that the use of herbal products becomes more and more widespread. The goal of this work was to examine the potential for the metabolism-based drug interaction arising from seven active components (danshensu, protocatechuic aldehyde, protocatechuic acid, salvianolic acid B, tanshinone...

Journal: :Molecules 2007
Aleksandra Simić Dragan Manojlović Dejan Segan Marija Todorović

We have investigated the electrochemical oxidation of a number natural phenolics (salicylic acid, m-hydroxybenzoic acid, p-hydroxybenzoic acid, protocatechuic acid, o-coumaric acid, m-coumaric acid, p-coumaric acid, caffeic acid, quercetin and rutin) using cyclic voltammetry. The antioxidant properties of these compounds were also studied. A structural analysis of the tested phenolics suggests ...

Journal: :Drug metabolism and disposition: the biological fate of chemicals 2015
Meijuan Li Fengqing Wang Yühong Huang Feifei Du Chenchun Zhong Olajide E Olaleye Weiwei Jia Yanfen Li Fang Xu Jiajia Dong Jian Li Justin B R Lim Buchang Zhao Lifu Jia Li Li Chuan Li

DanHong injection is a Danshen (Salvia miltiorrhiza roots)-based injectable solution for treatment of coronary artery disease and ischemic stroke. Danshen catechols are believed to be responsible for the injection's therapeutic effects. This study aimed to characterize systemic exposure to and elimination of Danshen catechols in human subjects, rats, and dogs receiving intravenous DanHong injec...

Journal: :Pharmacophore 2022

Sinapic acid biotransformation was studied and screened using eleven fungal cultures. Penicillium chermesinum AUMC 275, Aspergillus ochraceus 11328, Paecilomyces variotii 5618 showed positive results in the production of metabolites. resulted gallic after 10 days incubation with P. chermesinum, protocatechuic 7 A. ochraceus, ferulic 5 variotii. The investigated compounds' a

2015
Jessica L. di Gesso Jason S. Kerr Qingzhi Zhang Saki Raheem Sai Krishna Yalamanchili David O'Hagan Colin D. Kay Maria A. O'Connell

SCOPE Flavonoids are generally studied in vitro, in isolation, and as unmetabolized precursor structures. However, in the habitual diet, multiple flavonoids are consumed together and found present in the circulation as complex mixtures of metabolites. Using a unique study design, we investigated the potential for singular or additive anti-inflammatory effects of flavonoid metabolites relative t...

2013
Bernhard Schuster Michael W inter Karl Herrmann

The derivatives of hydroxybenzoic and hy­ droxycinnamic acids are widespread in the plant kingdom. A considerable number of these deriva­ tives are well known [1], Nevertheless there is only little existing information about the glucosides of these compounds and their distribution. Syringic acid-O-ß-D-glucoside was detected in Anodendron affine. [2], as well as /»-hydroxybenzoic acid-O-ß-D-gluc...

Journal: :Applied and environmental microbiology 2013
Natalia Jiménez José Antonio Curiel Inés Reverón Blanca de Las Rivas Rosario Muñoz

Lactobacillus plantarum is a lactic acid bacterium able to degrade tannins by the subsequent action of tannase and gallate decarboxylase enzymes. The gene encoding tannase had previously been identified, whereas the gene encoding gallate decarboxylase is unknown. Sodium dodecyl sulfate-polyacrylamide gel electrophoresis (SDS-PAGE) of gallic-acid induced L. plantarum extracts showed a 54-kDa pro...

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