PURPOSE Pseudoexfoliation syndrome (PEX), the most common identifiable cause of open-angle glaucoma, might affect the retinal hemodynamics. To test this, we compared retinal vessel diameter and glaucoma-related parameters between eyes with pseudoexfoliation material (PE+) and fellow unaffected (PE-) eyes of patients with clinically unilateral PEX. METHODS The medical records of 30 consecutive...

PURPOSE To study the relationship between pseudoexfoliation (PEX) and all-cause mortality in a population in which PEX is a common finding. METHODS Survival analyses were performed in a cohort of 760 residents 65-74 years of age, examined in a population survey in the municipality of Tierp, Sweden, 1984-86. To expand the cohort, participants in other studies in Tierp were enrolled. Additional...

INTRODUCTION Pseudoexfoliation syndrome (PEX) is a systemic disease involving the accumulation of pathological material deposits in the tissues of the anterior segment of the eye. The problem of modern ophthalmology is a quantitative assessment of the severity of PEX in the diagnosis and evaluation of the treatment progress in patients. MATERIAL AND METHOD For the purposes of this study, 52 i...

Pseudoexfoliation syndrome is an agerelated disease characterized by the pathological production and accumulation of an abnormal extracellular fibrillar material over ocular tissues as well as other tissues and organs in the body such as the lung, liver, kidney, gall bladder, and cerebral meninges. The specific pathogenesis of pseudoexfoliation syndrome and the exact chemical composition of the...

PURPOSE Pseudoexfoliation syndrome is a major risk factor for the development of glaucoma. Following recent reports of a strong association of coding variants in the lysyl oxidase-like 1 (LOXL1) gene with this syndrome but low penetrance and variable disease frequency between different populations, we aimed to identify additional genetic factors contributing to the disease. The clusterin (CLU) ...

PURPOSE To assess the prevalence of pseudoexfoliation (PEX) and its associations in a population-based setting. DESIGN Population-based, cross-sectional study. METHODS The Central India Eye and Medical Study included 4711 individuals. All study participants underwent a detailed ophthalmological examination. After medical pupil dilation, PEX was assessed by an experienced ophthalmologist usi...

The purpose of this study was to assess the prevalence of pseudoexfoliation syndrome and pseudoexfoliation glaucoma and to evaluate its association with open-angle glaucoma in patients attending the Department of Ophthalmology, Dr Tomislav Bardek General Hospital in Koprivnica, northwestern Croatia. This prospective study was conducted at Dr Tomislav Bardek General Hospital between December 201...

PURPOSE To determine the relationship between cerebro vascular disease and pseudoexfoliation syndrome. MATERIALS AND METHODS This cross-sectional case control study consisted of 50 patients with ischemic-type cerebro vascular disease and 50 control subjects. All subjects were investigated for diabetes mellitus and hypertension status and underwent a detailed ophthalmic examination. A diagnosi...

Pseudoexfoliation syndrome (PES) is a systemic disorder caused by progressive accumulation of extracellular material over various tissues. PES usually determines increased intraocular pressure, changes in the anatomical aspects of the optic nerve, and visual field alterations leading to the diagnosis of pseudoexfoliation glaucoma (PEG). Use of topical medical treatment usually leads to poor res...