Sodium 6{D(-)-a(4-hydroxyl-1,5 naphthyridine-3-carboxamido)phenylacetamido} penicillanate (PC-904) is a new semisynthetic penicillin with broadspectrum activity against gram-positive cocci and gram-negative bacilli. At a concentration of 1.56 ,ug/ml, it inhibited 100% of isolates of Proteus mirabilis, 89%o of Pseudomonas aeruginosa, 67% of Escherichia coli, and 45% of Enterobacter spp. At a con...

The aim of this paper was to determine in 32 patients from 4 different Mexican hospitals the frequency of opportunistic bacteria in the 2010 to 2011 time period. The patients were divided in 4 groups. Group 1 included 21 HIV positive patients with acute respiratory syndrome. Four HIV positive patients with tuberculosis symptoms were included in Group 2; two patients with tuberculosis symptoms a...

Ventilator-associated pneumonia (VAP) refers to pneumonia which occurs in people who required mechanical ventilation through an endotracheal or tracheostomy tube for at least 48 hours. The study includes patients of pneumonia who were on mechanical ventilation for more than 48 hours and admitted to the intensive care unit (ICU). During the study period 48 patients developed VAP out of which 51 ...

In a period of two years, 865 strains of Gram-negative bacilli other than Pseudomonas aeruginosa isolated from burns were identified by a range of tests. The commonest species were Proteus mirabilis, Escherichia coli, and Enterobacter cloacae. Many strains of Klebsiella aerogenes, Enterobacter aerogenes, and Bacterium anitratum were also found.A large proportion of the strains were tested for s...

aims: the internal unit and icu of hospitals are a suitable environment for growing of bacteria such as staphylococcus epidermidis, pseudomonas and acinetobacters. the aim of this study was to evaluate the efficacy of using disinfectants on bacterial remove in isfahan city, iran, hospitals. instrument & methods: this descriptive study was performed in isfahan city, iran, hospitals in 2015. 200 ...

BACKGROUND Sepsis is a major cause of mortality and morbidity in newborns affecting both developed and developing countries accounting a quarter around one million deaths per annum. OBJECTIVE This study was aimed to assess the prevalence of neonatal sepsis, culture isolates, pattern, antibiotic sensitivity and drug prescribing pattern. METHODS In present prospective study, 48 neonates admit...

The in vitro activity of a new semisynthetic penicillin, piperacillin, was determined against 577 clinical isolates of gram-positive cocci and gram-negative bacilli. A concentration of 12.5 mug/ml inhibited 92% of isolates of Pseudomonas aeruginosa, 82% of Serratia marcescens, 73% of Escherichia coli, 61% of Klebsiella spp., and 42% of Enterobacter spp. Most Proteus spp. were extremely suscepti...

The in vitro activities of two new beta-lactam antibiotics, moxalactam disodium (LY 127935) and cefotaxime (HR-756), were compared with cefoxitin, cefamandole, cefuroxime, cephalothin, and, in some instances, carbenicillin, gentamicin, and amikacin against aerobic gram-negative bacilli. Test isolates included normally cephalosporin-resistant members of the Enterobacteriaceae and Pseudomonas spp...

Toxin-antitoxin (TA) systems are prevalent in bacteria and archaea. Although not essential for normal cell growth, TA systems are implicated in multiple cellular functions associated with survival under stress conditions. Clinical strains of bacteria are currently causing major human health problems as a result of their multidrug resistance, persistence and strong pathogenicity. Here, we presen...

INTRODUCTION Sepsis is a systemic inflammatory response related to high mortality rates in the hospital environment. Delayed etiological diagnosis and inadequate antimicrobial therapy are associated with treatment failures. Molecular tests based on polymerase chain reaction are regarded as faster and more accurate procedures than culture techniques for microbial identification, providing a high...