OBJECTIVE To test the hypothesis that extended postoperative antibiotic cover would reduce the incidence of pulmonary complications in patients undergoing major head and neck surgery with tracheostomy. DESIGN A prospective, randomized, controlled trial was carried out to determine the efficacy of an extended course (5 days) of intravenous amoxicillin-clavulanic acid in reducing the rate of at...

Lung transplantation is a therapeutic option for the treatment of advanced lung disease. The risk pulmonary infections increased in transplant recipients. We report case coinfection with Mycobacterium tuberculosis and Nocardia species recipient.

Infection with novel coronavirus (SARS-CoV-2) remains one of the most important pandemics till present, becoming an equation several unknowns, them being associated fungal infections. Pulmonary mycoses have increased incidence and mortality, common germ identified among cases COVID-19 is Aspergillus spp. Due to discrepancies in defining diagnostic criteria, but also nonspecific clinical-imaging...

a Scottish Centre for Respiratory Research, University of Dundee, Ninewells Hospital and Medical School, Dundee DD1 9SY, United Kingdom b Mayo Clinic College of Medicine, Rochester, MN, USA c Laboratory of Innovation in Therapies, Education and Bioproducts (LITEB), Oswaldo Cruz Institute IOC, Fiocruz, Rio de Janeiro, Brazil d Hospital Universitario de Monterrey, Centro de Investigación, Prevenc...

Pulmonary disease due to EM occurs worldwide, and its prevalence has increased as a consequence of the HIV pandemic. It is not often detected in the tropics owing to a lack of laboratory facilities, but when sought it has been found. In addition to HIV infection certain occupations such as mining render the work force more susceptible to disease and calls for a revision of working conditions. R...

The idea is now behind us that infections, be they of the lung or any other part of the body, are a group of conditions that have been vanquished by advances in medical science. The threat from infection to the human host is undiminished and may even be increasing [1]. The lung with its interface to the outside world remains one of the main battlefields where this interaction between man and mi...

It is generally agreed that a bacteriophage-associated phenomenon was first unambiguously observed one-hundred years ago with the findings of Twort in 1915. This was independently followed by complementary observations by d'Hérelle in 1917. D'Hérelle's appreciation of the bacteriophage phenomenon appears to have directly led to the development of phages as antibacterial agents within a variety ...

The increasing burden of respiratory diseases caused by microbial infections poses an immense threat to global health. This review focuses on the various types biofilms that affect system and cause pulmonary infections, specifically bacterial biofilms. article also sheds light current strategies employed for treatment such infection-causing potential nanocarriers as effective modality is discus...

Dr. Lipatov, Dr. Patel, Dr. Lat, and Dr. Shakespeare are Internal Medicine Residents at Scott and White Memorial Hospital. Dr. Wang and Dr. Prakash are Physicians at the Central Texas Veterans Health Care System; all in Temple, Texas. Correspondence: Dr. Lipatov (Kirill.Lipatov @BSWHealth.org) Mucorales fungi are ubiquitous organisms commonly inhabiting soil and can cause opportunistic infectio...

BACKGROUND Pulmonary Staphylococcus aureus (S. aureus) infections occur early in a high percentage of cystic fibrosis (CF) patients and it is believed that these infections facilitate further colonization of CF lungs with Pseudomonas aeruginosa (P. aeruginosa). Previous studies demonstrated a marked reduction of sphingosine in tracheal and bronchial epithelial cells in CF compared to wild type ...