Dental Caries affects approximately 90% of the world's population. At present, the clinical treatment for dental caries is root canal therapy. This treatment results in loss of tooth sensitivity and vitality. Tissue engineering can potentially solve this problem by enabling regeneration of a functional pulp tissue. Dental pulp stem cells (DPSCs) have been shown to be an excellent source for pul...

Stepwise excavation is an old concept but has become a research subject more, in recent years. It is a conservative approach to treat deep dental caries lesions where the exposure of the pulp is probable. In case of pulpal exposure, Root Canal Therapy (RCT) is the routine treatment method. However, RCT is an expensive treatment, especially in countries like Iran where most of the dental treatme...

Scientific advances in the creation of restorative biomaterials, in vitro cell culture technology, tissue grafting, tissue engineering, molecular biology and the human genome project provide the basis for the introduction of new technologies into dentistry. Non-vital infected teeth have long been treated with root canal therapy (for mature root apex) and apexification (for immature root apex), ...

BACKGROUND Several medicaments have been used to devitalize remaining pulp or maintain pulp vitality and promote healing. Based on pulpal biocompatibility and good sealing ability, a growing interest in more biocompatible materials promotes mineral trioxide aggregate (MTA) as an alternative to traditional medicaments. Uniquely, MTA can preserve pulpal health predictably and promote healing with...

Pulp capping is a procedure that comprises adequate protection of the pulp tissue exposed to the oral environment, aiming at the preservation of its vitality and functions. This study evaluated the response of the dental pulps of dog teeth to capping with mineral trioxide aggregate (MTA) or calcium hydroxide P.A. For that purpose, 37 teeth were divided into two groups, according to the capping ...

INTRODUCTION Pulpal reactions after acute dental injury have been puzzling for many clinicians. The management of dental trauma and an understanding of clinical and treatment factors in outcomes arose from multivariate statistical analyses of archive material from Copenhagen. METHODS The aim of this article was to review the works of this period with respect to pulpal reaction after acute mec...

INTRODUCTION The aim of this randomized clinical trial was to compare the histologic pulp tissue response to one-step direct pulp capping (DPC) and miniature pulpotomy (MP) with mineral trioxide aggregate (MTA) after application of dexamethasone in healthy human premolars. METHODS AND MATERIALS Forty intact premolars from 10 orthodontic patients, were randomly chosen for DPC (n=20) or MP (n=2...

Regenerative endodontic procedures are the emerging techniques for the restoration of functional pulp and dentine. The case report presented here describes the management of a symptomatic mandibular first molar with an immature apex and necrotic pulp in a 9 year old child. The tooth was tender on percussion and palpation and elicited a negative response to sensibility testing. A regenerative en...

crown fractures account for the majority of dental traumas if handled properly, prognosis of the pulp following a traumatic crown fracture can be favorable. the present case report focuses on the treatment of a traumatized mature permanent incisor with exposed pulp that was treated with the novel technique of miniature pulpotomy using calcium-enriched mixture (cem) cement. one-year follow-up re...

INTRODUCTION Similar to other tissues, the dental pulp mounts an inflammatory reaction as a way to eliminate pathogens and stimulate repair. Pulp inflammation is prerequisite for dentin pulp complex repair and regeneration; otherwise, chronic disease or pulp necrosis occurs. Evaluation of pulp inflammation severity is necessary to predict the clinical success of maintaining pulp vitality. Clini...