INTRODUCTION Acute kidney injury (AKI) is a relatively frequent complication after coronary artery bypass graft surgery (CABG). We compared the off- and on-pump CABG procedures with respect to changes in renal function as reflected by levels of urine neutrophil gelatinase-associated lipocalin (UrNGAL). METHODS In a prospective design, we studied patients who underwent CABG, off- or on-pump, w...

OBJECTIVE Previous studies comparing off-pump coronary artery bypass surgery (OPCABG) to conventional techniques utilizing cardiopulmonary bypass (CABG-CPB) have failed to provide patient selection guidelines. We sought to determine guidelines, attempting to rectify the limitations of previous studies. METHODS AND RESULTS A retrospective analysis of prospectively collected data from the Socie...

OBJECTIVE To examine explanations of differences in utilization rates of a newly reintroduced technique - off-pump coronary artery bypass grafting (CABG) - between racial minorities and Whites. METHOD The study was based on 15,313 CABG patients in the New York State Cardiac Surgery Reporting System covering all cardiac surgeons providing off-pump CABG in New York State. We estimated cross sec...

INTRODUCTION To examine whether or not off-pump CABG (Coronary Artery Bypass Reduce) reduces the incidence of AF after cardiac surgery. METHODS The study was carried out in 939 consecutive coronary artery disease patients with sinus rhythm from which 383 patients underwent off-pump CABG, and 556 patients were operated through on-pump CABG. All patients were monitored postoperatively during in...

Release After Off-Pump Versus On-Pump Coronary Surgery In a recent study by Selvanayagam and colleagues aimed at evaluating reversible and irreversible myocardial injury in patients undergoing off-pump (OP-) versus on-pump (P-) coronary artery bypass surgery (CABG),1 the authors documented a similar incidence and magnitude of new irreversible myocardial injury in both groups, despite the greate...

OBJECTIVES Patients undergoing coronary bypass grafting (CABG) are at higher risk if they suffer from atrial fibrillation (AF). It was suggested that performing CABG without the use of cardiopulmonary bypass (off-pump) would reduce perioperative risk. We assessed the influence of preoperative AF on outcome in a randomized cohort of patients above the age of 75 undergoing either on-pump or off-p...

BACKGROUND Octogenarians are a challenging group of patients referred for cardiac surgery. The aim of this study is to assess early outcomes of coronary artery bypass grafting (CABG) performed in the elderly population. METHODS We performed a meta-analysis of all published observational studies comparing early results of conventional CABG surgery and off-pump CABG surgery in patients aged 80 ...

BACKGROUND Neurocognitive impairment can be a debilitating complication after coronary artery bypass graft surgery (CABG). Cardiopulmonary bypass, in particular, cerebral emboli, has been implicated. We compared neurocognitive function and cerebral emboli in patients undergoing on-pump and off-pump CABG. METHODS 212 patients admitted for CABG were randomly assigned to on-pump (n = 104) or off...

BACKGROUND Gastrointestinal (GI) complications following coronary artery bypass grafting (CABG), although infrequent, are associated with significant morbidity and mortality. It has been suggested that systemic inflammatory response plays an important role in these complications. Cardiopulmonary bypass (CPB) is well known to cause increased systemic inflammation, and therefore it has been propo...