نتایج جستجو برای: pxo2

تعداد نتایج: 87  

2010
Silke R. Klee Elzbieta B. Brzuszkiewicz Herbert Nattermann Holger Brüggemann Susann Dupke Antje Wollherr Tatjana Franz Georg Pauli Bernd Appel Wolfgang Liebl Emmanuel Couacy-Hymann Christophe Boesch Frauke-Dorothee Meyer Fabian H. Leendertz Heinz Ellerbrok Gerhard Gottschalk Roland Grunow Heiko Liesegang

Anthrax is a fatal disease caused by strains of Bacillus anthracis. Members of this monophyletic species are non motile and are all characterized by the presence of four prophages and a nonsense mutation in the plcR regulator gene. Here we report the complete genome sequence of a Bacillus strain isolated from a chimpanzee that had died with clinical symptoms of anthrax. Unlike classic B. anthra...

2013
Simon Silver

Why would one want to sequence the genomes of 94 additional, mostly soil and water isolates of Bacillus cereus sensu lato (1)? The answer is of course to be able to make a rapid analysis during a bioterrorism event, to develop a portable kit for the rapid identification of anthrax spores (by proteomic analysis), and to determine their precise origin (by means of DNA genomic polymorphisms). The ...

2008
Prabir K. Dutta Andrew J. Phipps Mamoru Yamaguchi William C. Schumacher

Rapid and accurate detection of Bacillus anthracis, the causative agent of anthrax, remains an active area of research due to the continued threat of bioterrorist attack. The ability to differentiate Bacillus anthracis spores from spores belonging to other Bacillus species is important for the development of spore-based detection methods. Furthermore, not all Bacillus anthracis strains are full...

Journal: :Pathogens 2023

(1) Background: Bacillus cereus biovar anthracis (Bcbva) was the causative agent of an anthrax-like fatal disease among wild chimpanzees in 2001 Côte d’Ivoire. Before this, there had not been any description caused by typically avirulent cereus. Genetic analysis found that B. acquired two plasmids, one a pXO1-like toxin producing plasmid and other pXO2-like encoding capsule. Bcbva animal fatali...

2009
Yih-Ling Tzeng

Sporulation initiation in Bacillus species is controlled by an extended version of two-component signal transduction systems, termed phosphorelay (4). The cascade of His3Asp3 His3Asp phosphotransfer is typically initiated by the ATPdependent autophosphorylation of the histidine kinase domain. In this issue, Scaramozzino et al. (11) reported that a sporulation histidine kinase, BA2291, in Bacill...

Journal: :The Indian journal of medical research 2003
K S R Sastry U Tuteja K Bala Krishna H V Batra

BACKGROUND & OBJECTIVE Anthrax has been reported from almost every country and India is endemic for this disease. There is considerable under reporting of the disease because of lack of microbiological facilities and diagnostic reagents. In India only conventional methods which have limitations, are being used to diagnose the disease. Hence the aim of this study was to isolate and purify protec...

Journal: :Journal of bacteriology 1997
P Keim A Kalif J Schupp K Hill S E Travis K Richmond D M Adair M Hugh-Jones C R Kuske P Jackson

Bacillus anthracis causes anthrax and represents one of the most molecularly monomorphic bacteria known. We have used AFLP (amplified fragment length polymorphism) DNA markers to analyze 78 B. anthracis isolates and six related Bacillus species for molecular variation. AFLP markers are extremely sensitive to even small sequence variation, using PCR and high-resolution electrophoresis to examine...

2015
Hirohito Ogawa Daisuke Fujikura Miyuki Ohnuma Naomi Ohnishi Bernard M. Hang'ombe Hitomi Mimuro Takayuki Ezaki Aaron S. Mweene Hideaki Higashi

Anthrax is an important zoonotic disease worldwide that is caused by Bacillus anthracis, a spore-forming pathogenic bacterium. A rapid and sensitive method to detect B. anthracis is important for anthrax risk management and control in animal cases to address public health issues. However, it has recently become difficult to identify B. anthracis by using previously reported molecular-based meth...

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